Cyclosporine

Jun 23, 2019 by in General Surgery Comments Off on Cyclosporine

Keywords Cyclosporine, CsA, Neoral, Sandimmune, PISCES, PREWENT   Key points • Cyclosporine (CsA) is a highly effective treatment option for patients with moderate-to-severe plaque psoriasis with a rapid onset of…

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Acitretin

Jun 23, 2019 by in General Surgery Comments Off on Acitretin

Keywords Acitretin, Etretinate, Phototherapy, PUVA, Broadband UV-B, Narrowband UV-B, Teratogenic, Hyperlipidemia   Key points • Acitretin is an effective agent for the treatment of plaque psoriasis and is often used…

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Methotrexate

Jun 23, 2019 by in General Surgery Comments Off on Methotrexate

Keywords Methotrexate, MTX, Folate antagonist, CHAMPION, RESTORE1   Key points • Methotrexate (MTX) remains a safe and effective modality for the treatment of severe, recalcitrant psoriasis when used appropriately. •…

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Psoralen-Ultraviolet Light A Therapy

Jun 23, 2019 by in General Surgery Comments Off on Psoralen-Ultraviolet Light A Therapy

Keywords Psoralen-UV-A, PUVA, Photochemotherapy, Psoriasis   Key points • Psoralen-UV-A (PUVA) photochemotherapy involves use of either an oral or topical psoralen followed by exposure to long-wave UV-A radiation. This combination…

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Ultraviolet B Phototherapy

Jun 23, 2019 by in General Surgery Comments Off on Ultraviolet B Phototherapy

Keywords Phototherapy, Narrowband UV-B, UV therapy, Psoriasis, Excimer laser   Key points • Phototherapy with UV light can be used in the treatment of several cutaneous disorders. • Phototherapy is…

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Overview of Psoriasis

Jun 23, 2019 by in General Surgery Comments Off on Overview of Psoriasis

Keywords Psoriasis, Plaque psoriasis, Clinical subtypes, Pustular psoriasis, Nail psoriasis, Comorbidities   Key points • Today, psoriasis is a global disease causing significant impairment in quality of life, disfiguring morbidity,…

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Nerve transfers

Jun 15, 2019 by in General Surgery Comments Off on Nerve transfers

Synopsis ■ Nerve injuries are often devastating, with associated pain and impaired function. ■ Motor nerve injuries must be managed expeditiously, because regenerating axons must reach target muscle prior to…

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Back reconstruction

Jun 15, 2019 by in General Surgery Comments Off on Back reconstruction

Synopsis ■ Reconstruction of the soft tissues of the back at first may seem to be a daunting task compounded by large wounds, unfamiliar and segmental anatomy, radiation, hardware, and…

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Cleft lip repair

Jun 15, 2019 by in General Surgery Comments Off on Cleft lip repair

Synopsis Unilateral lip repair Principles of unilateral cleft lip repair ▪ Presurgical nasoalveolar molding. ▪ Modification of surgical techniques. ▪ Mohler rotation incision. ▪ Mucosal flaps for nasal floor reconstruction,…

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Lower extremity reconstruction

Jun 15, 2019 by in General Surgery Comments Off on Lower extremity reconstruction

Synopsis ■ The reconstructive surgery for the lower extremity has evolved from a staged approach to proving best solutions for functional and cosmetic outcome. ■ This chapter covers the classical…

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