Epidermolysis Bullosa Nevi

Feb 12, 2018 by in Dermatology Comments Off on Epidermolysis Bullosa Nevi

Epidermolysis bullosa (EB) nevi are large, eruptive, asymmetrical, often irregularly pigmented melanocytic lesions. Such nevi may give rise to small satellite nevi surrounding the primary nevus, and thus frequently manifest…

read more

Understanding the Pathogenesis of Recessive Dystrophic Epidermolysis Bullosa Squamous Cell Carcinoma

Feb 12, 2018 by in Dermatology Comments Off on Understanding the Pathogenesis of Recessive Dystrophic Epidermolysis Bullosa Squamous Cell Carcinoma

Patients with recessive dystrophic epidermolysis bullosa develop numerous life-threatening skin cancers. The reasons for this remain unclear. Parallels exist with other scarring skin conditions, such as Marjolin ulcer. We summarize…

read more

Alopecia in Epidermolysis Bullosa

Feb 12, 2018 by in Dermatology Comments Off on Alopecia in Epidermolysis Bullosa

Hair abnormalities observed in epidermolysis bullosa (EB) are of variable severity and include mild hair shaft abnormalities, patchy cicatricial alopecia, cicatricial alopecia with a male pattern distribution, and alopecia universalis….

read more

Nail Involvement in Epidermolysis Bullosa

Feb 12, 2018 by in Dermatology Comments Off on Nail Involvement in Epidermolysis Bullosa

Nail abnormalities are a common feature in most subtypes of epidermolysis bullosa (EB), and they recently have been included among the criteria for scoring EB severity. Trauma undoubtedly contributes to…

read more

Animal Models of Epidermolysis Bullosa

Feb 12, 2018 by in Dermatology Comments Off on Animal Models of Epidermolysis Bullosa

For more than 2 decades, animal models have been used to clarify the pathogenic mechanisms of human diseases and develop new therapeutics for these diseases. Several therapies for human diseases…

read more

Lethal Acantholytic Epidermolysis Bullosa

Feb 12, 2018 by in Dermatology Comments Off on Lethal Acantholytic Epidermolysis Bullosa

Lethal acantholytic epidermolysis bullosa (LAEB) is an autosomal recessive disorder caused by mutations in the gene encoding the desmosomal protein, desmoplakin (DSP). It is recognized as a distinct form of…

read more
Get Clinical Tree app for offline access