Disorders of Pigmentation
For diagnosis Clinical evaluation Biopsy rarely needed for confirmation Genetic screen for mucopolysaccharidoses in extensive cases For treatment Tincture of time—most lesions resolve by age 6 years The most common…
Infectious Diseases: Superficial Fungal Infections
Fig. 16.1 Tinea corporis. Erythematous plaque with elevated border Fig. 16.2 Majocchi’s granuloma. Folliculocentric papules and pustules within a thin plaque with an expanding, elevated border on the cheek of…
Hereditary Disorders of the Dermis
Fig. 6.1 Ehlers-Danlos syndrome. Increased skin laxity Fig. 6.2 Ehlers-Danlos syndrome. Widened fish-mouth scar with atrophic skin on the leg The clinical features of vascular EDS can be very subtle,…
Inborn Metabolic Disorders and Endocrine Disorders
Fig. 23.1 Alternating bands of light and dark color along hair fibers indicative of periods of protein deficiency in phenylketonuria (Courtesy of Dr. Maureen Rogers) Specific Investigations Newborn screening (tandem…
Management of Skin Disorders of the Newborn
For diagnosis Clinical–facial eruption of pustules that begins at age 5–30 days. It resembles neonatal acne but lacks comedones and is associated with colonization with Malassezia Giemsa stain–yeast form, neutrophils…
Genodermatoses and Basement Membrane Zone Diseases
Fig. 13.1 Clinical presentation of patients with Epidermolysis Bullosa. (a) Typical blistering leading to chronic wounds in a patient with RDEB. (b) Blisters on the foot at the sites of…
Photosensitivity and Photoreaction
Fig. 21.1 Solar urticaria on back soon after sun exposure Management Strategies General management of solar urticaria includes use of protective clothing, broad spectrum UVA/UVB sunscreens, and avoidance of exposure…
Cutaneous Manifestations of Psychiatric Disorders and Management
Medication Mechanism Starting dose Max dose Weight gain Sedation FDA approval in children Evidence level Notes Risperidone (Risperdal) SGA 0.25 mg 6 mg ++ + SCZ age 13–17, BP 1…
Infectious Diseases: Deep Fungal Infections
Fig. 17.1 Lymphocutaneous sporotrichosis. Erythematous nodule and ulceration present along the lymphatics of the upper extremity (Photo courtesy of Sylvia Hsu, MD) Chromomycosis is caused by inoculation of a dematiaceous…
Vascular Disorders and Anomalies
For diagnosis PHACE evaluation if segmental on head, neck, upper chest MRI/MRA head/neck/upper chest Cardiac examination ECHO and EKG Ophthalmologic examination LUMBAR evaluation if segmental on lower part of the…
