In this chapter proliferations derived from vascular endothelial cells, fibroblasts, myofibroblasts, smooth muscle cells, Schwann cells, and lipocytes are reviewed. Also discussed are several neoplasms of cells invading or aberrantly…
Epidermal Nevi Epidermal nevi are hamartomatous growths of the epidermis that are present at birth in about half of patients or develop early in childhood. The term epidermal nevus includes…
Viruses are obligatory intracellular parasites. The structural components of a viral particle (virion) consist of a central core of nucleic acid, a protective protein coat (capsid), and (in certain groups…
The genetic basis for common diseases such as atopic dermatitis and psoriasis, in addition to rare diseases, has been partially elucidated. Some genetic disorders are explained by mutations in a…
The major groups of animals responsible for bites, stings, and parasitic infections in humans belong to the phyla Arthropoda, Chordata, Cnidaria (formerly Coelenterata), Nemathelminthes, Platyhelminthes, Annelida, and Protozoa. This chapter…
Diseases of the Hair Normal human hairs can be classified according to cyclic phases of growth. Anagen hairs are growing hairs; catagen hairs are those undergoing transition from the growing…
Amyloidosis Amyloid is a material deposited in the skin and other organs that is eosinophilic, homogeneous, and hyaline in appearance. It represents beta-pleated sheet forms of various host-synthesized molecules processed…
In noninherited chronic blistering (vesicular or bullous) dermatoses, the cause of blistering is usually an autoimmune reaction, and the location where antibodies bind determines the clinical, histologic, and immunofluorescent pattern….
Raynaud Phenomenon and Raynaud Disease Raynaud phenomenon is characterized by episodic, recurrent vasospasm of the fingers and toes resulting in white, blue, and red discoloration provoked by cold or stress….
The visible pigmentation of the skin or hair is a combination of the amount of melanin, type of melanin (eumelanin vs. pheomelanin), degree of vascularity, presence of carotene, and thickness…
