Perforating Diseases
Abstract The perforating diseases are a group of disorders in which papulonodules develop due to transepidermal elimination of connective tissue or other substances. Two prototypes are reactive perforating collagenosis (RPC),…
Atrophies of Connective Tissue
Abstract Atrophies of the skin are caused by a diminution or loss of collagen and/or elastic fibers. These disorders range from common conditions, such as striae distensiae, to those conditions…
Oral Disease
Abstract Examination of the oral soft and hard tissues may reveal signs of developmental anomalies, infectious or inflammatory conditions, and neoplastic processes. Alterations of the oral mucosa may also be…
Biology of the Extracellular Matrix
Abstract Extracellular matrices (ECMs) consist of highly organized networks of collagens, elastin, glycoproteins, and proteoglycans. In addition to establishing tissue architecture and providing mechanical strength, ECMs are biologically active, regulating…
Foreign Body Reactions
Abstract When implanted or injected into the skin, inorganic and high-molecular-weight organic materials can elicit a range of inflammatory reactions, from granulomatous to lichenoid to pseudolymphomatous. Less commonly, reactions resemble…
Photodermatologic Disorders
Abstract Pathologic reactions of the skin to light can arise from multiple etiologies including: immunologic photodermatoses, e.g. polymorphous light eruption, solar urticaria, actinic prurigo, hydroa vacciniforme, and chronic actinic dermatitis;…
Protozoa and Worms
Abstract Protozoal and helminth infections are major causes of tropical disease in many parts of the world. For some of the conditions, the clinical presentations differ depending on the geographic…
Skin Signs of Abuse
Abstract Physical, psychological, and sexual abuse may occur in any cultural environment. Although abuse is not limited to particular age groups, this chapter focuses on abuse and neglect inflicted upon…
Histiocytoses
Abstract This chapter covers the histiocytoses with emphasis on Langerhans cell histiocytosis (LCH) and many of the disorders comprising the large group of diseases referred to as non-Langerhans cell histiocytoses…
Sexually Transmitted Infections
Abstract Every day, more than 1 million people worldwide are newly infected with sexually transmitted infections (STIs), leading not just to an increase in morbidity and mortality, but also a…
