Complementary and Alternative Approaches II
Key points • A review of a variety of alternative therapies for atopic dermatitis (AD) is the focus of this chapter. Among those reviewed are acupuncture, cupping, and herbal therapies,…
Complementary and Alternative Approaches I
Key points • Current first-line conventional treatments for atopic dermatitis include topical corticosteroids, emollients, and topical and/or systemic immunomodulators (e.g., dupilumab). • However, a majority of patients with atopic dermatitis…
Itch and Pain Treatments
Key points • Itch and pain are key symptoms of atopic dermatitis (AD) that significantly affect quality of life; various classes of treatment aim to reduce these symptoms. • Nonpharmacologic…
Emerging Targeted Treatments
Key points • This chapter provides an overview of the pathogenesis of atopic dermatitis and the key mediators that are of therapeutic interest. • As we acquire more knowledge into…
Skin Barrier Repair
Key points • Moisturizers help with skin barrier repair and continue to be the mainstay of maintenance treatment and prevention of flares in atopic dermatitis (AD). • Though greasier moisturizer…
Cellular Factors
Key points • Atopic dermatitis (AD) is a complex disease with various types of leukocytes involved in its pathology. • Multiple subsets of CD4 + helper T cells, which are…
Therapeutic Guideline Overview
Key points • Multiple clinical guidelines, consensus statements, and expert management recommendations have been published for atopic dermatitis. • Most prominent guidelines are from the American Academy of Dermatology and…
Topical Therapies
Key points • Optimal bathing practices can improve atopic dermatitis (AD) symptoms and limit disease flares. Best practices include daily bathing for less than 10 minutes in lukewarm water, utilizing…
Clinical Evidence: Internal Factors
Key points • Less than 50% of patients affected with atopic dermatitis have a genetic mutation of the skin barrier protein, filaggrin. Thus additional contributing factors, barrier defects, and beyond…
Neurosensory Mechanisms
Key points • Both itch and pain are very frequent symptoms in patients with atopic dermatitis, with a prevalence of more than 50%. • Patients with atopic dermatitis show neuronal…
