Fig. 24.1 A baby with failure to thrive and poor wound healing after delayed separation of umbilical stump Fig. 24.2 Treatment-resistant thrush in undifferentiated immunodeficiency disorder Table 24.1 Clinical cutaneous…
Trichorrhexis invaginata Microscopic examination of hair shaft: bamboo hair. Hair shaft with multiple knots resembling the ball-and-cup joint of bamboo Dermoscopy: nodular swellings at irregular intervals, ball-shaped knots similar to…
Inherited ichthyoses Non-syndromic Mode of inheritance Genes Common ichthyoses Ichthyosis vulgaris Autosomal semi dominant FLG Autosomal recessive congenital ichthyosis Harlequin ichthyosis Autosomal recessive ABCA12 Lamellar ichthyosis Autosomal recessive TGM1/NIPAL4/ALOX12B/ABCA12 Congenital…
For diagnosis Clinical evaluation Biopsy rarely needed for confirmation Genetic screen for mucopolysaccharidoses in extensive cases For treatment Tincture of time—most lesions resolve by age 6 years The most common…
Fig. 16.1 Tinea corporis. Erythematous plaque with elevated border Fig. 16.2 Majocchi’s granuloma. Folliculocentric papules and pustules within a thin plaque with an expanding, elevated border on the cheek of…
Fig. 6.1 Ehlers-Danlos syndrome. Increased skin laxity Fig. 6.2 Ehlers-Danlos syndrome. Widened fish-mouth scar with atrophic skin on the leg The clinical features of vascular EDS can be very subtle,…
Fig. 23.1 Alternating bands of light and dark color along hair fibers indicative of periods of protein deficiency in phenylketonuria (Courtesy of Dr. Maureen Rogers) Specific Investigations Newborn screening (tandem…
For diagnosis Clinical–facial eruption of pustules that begins at age 5–30 days. It resembles neonatal acne but lacks comedones and is associated with colonization with Malassezia Giemsa stain–yeast form, neutrophils…
Fig. 13.1 Clinical presentation of patients with Epidermolysis Bullosa. (a) Typical blistering leading to chronic wounds in a patient with RDEB. (b) Blisters on the foot at the sites of…
Fig. 21.1 Solar urticaria on back soon after sun exposure Management Strategies General management of solar urticaria includes use of protective clothing, broad spectrum UVA/UVB sunscreens, and avoidance of exposure…
