Abstract Several systemic disorders, including inherited and inflammatory disorders, may manifest with both cardiovascular and cutaneous findings. In addition, certain cutaneous findings, such as psoriasis, a diagonal earlobe crease, and…
Abstract Cutaneous fungal infections with systemic involvement can be divided clinically into subcutaneous mycoses and systemic mycoses, based on mode of acquisition and the extent of tissue involvement. Subcutaneous mycoses…
Abstract Protozoan organisms continue to represent a major disease burden worldwide. Diseases such as toxoplasmosis affect much of the population, and other diseases like leishmaniasis have undergone a resurgence in…
Abstract Cutaneous bacterial infections are important causes of morbidity. Meticillin-resistant staphylococcal infections present as abscess or folliculitis, and drainage remains the key component of management. Lyme disease presents with annular…
Abstract There are numerous cutaneous manifestations of liver disease. This chapter focuses on the most common cutaneous manifestations of hepatic disease including diagnosis, management, and therapy. KeywordsCryoglobulins, Hemochromatosis, Hepatic, Hepatitis,…
Abstract Viruses produce a variety of cutaneous changes, including morbilliform (measles-like), papular, and vesicular eruptions. It is often difficult to distinguish viral exanthems from morbilliform drug eruptions; however, subtle distinguishing…
Abstract Gastrointestinal diseases have many cutaneous associations. Gastrointestinal hemorrhage may be associated with the peau d’orange plaques of pseudoxanthoma elasticum or the macular telangiectases of hereditary hemorrhagic telangiectasia. Adenomatous polyposis…
Abstract A variety of vascular lesions can serve as cutaneous signs of systemic disease. Although telangiectasias are common, they occasionally represent markers for autoimmune connective tissue diseases and genetic conditions…
Abstract Porphyrias are a group of inherited or acquired metabolic disorders manifested by cutaneous photosensitivity, episodic neurovisceral dysfunctions, or both. Each porphyria is caused by reduced activity (or in one…
Abstract Cutaneous xanthomas may signal an underlying lipid, metabolic, or hematologic abnormality, so accurate diagnosis is essential. The clinical presentations of different types of xanthomas including eruptive, tuberous, planar, and…
