Abstract This chapter discusses benign epidermal tumors, ranging from extremely common lesions (e.g. seborrheic keratoses) to less common (e.g. disseminated superficial actinic porokeratosis) to unusual or rare (e.g. warty dyskeratoma,…
Abstract This chapter focuses on disorders characterized by dysfunction of skin vasculature, including livedo reticularis, flushing, erythromelalgia, and nevus anemicus. In addition, vascular ectasias such as telangiectasias and venous lakes…
Abstract The blood vessels of the skin are involved in the control of body temperature and they provide a conduit for the supply of nutrients and oxygen to the skin…
Abstract The non-infectious granulomatous diseases discussed in this chapter are unified by similar histologic findings despite having disparate, often unknown, causes. They are defined by their cutaneous inflammatory infiltrate, consisting…
Abstract Oncogenes act in a dominant fashion and gain-of-function results in increased cellular proliferation. Tumor suppressor genes act in a recessive fashion and loss of normal function results in uncontrolled…
Abstract This chapter describes disorders in which there is an increase in the amount of collagen within the skin, followed by those with an increase in elastic fibers. The first…
Abstract Panniculitis represents infiltration of the subcutaneous tissue by inflammatory cells, although the term has also been applied to neoplastic infiltration. Typically there is deep induration or swelling of the…
Abstract Heritable disorders of connective tissue comprise a phenotypically diverse group of conditions that often have multisystem involvement. These disorders can result from mutations in genes encoding structural elements of…
Abstract The perforating diseases are a group of disorders in which papulonodules develop due to transepidermal elimination of connective tissue or other substances. Two prototypes are reactive perforating collagenosis (RPC),…
