Despite the many therapies available, no treatment has been shown to increase survival in patients with mycosis fungoides. It is therefore inadvisable to treat stage IA disease with a medication…
Sentinel lymph node sampling is becoming routinely performed in the care of these patients and aids in staging of the disease. If the patient has a positive sentinel lymph node…
Histology: Merkel cell carcinoma is a neuroendocrine tumor. The tumor is composed of small, uniformly shaped, basophilic-staining cells. The tumor is poorly circumscribed and grows in an infiltrative pattern between…
At the other end of the spectrum is the Sézary syndrome. This is an erythrodermic variant of mycosis fungoides with peripheral blood involvement. Circulating Sézary cells are the hallmark of…
Lentigo maligna melanoma is most often seen on the face of patients in their fifth to seventh decades of life, especially in those with a considerable sun exposure history. This…
Histology: The tumor is typically a cup-shaped exophytic nodule that has a prominent keratin-filled plug. The borders of the tumor are well circumscribed. The tumor is symmetric. Neutrophilic abscesses within…
Histology: Dermatofibrosarcoma protuberans shows an infiltrative growth pattern. It invades the subcutaneous fat tissue. The tumor cells can be seen encasing adipocytes. The tumor is poorly circumscribed, and its borders…
Treatment: The prognosis for extramammary Paget’s disease depends on the stage of the tumor. Disease that is localized to the skin has an excellent prognosis. The treatment of choice is…
Histology: Biopsies of Kaposi’s sarcoma show many characteristic findings. The promontory sign is often seen; it is represented by plump endothelial cells jutting into the lumen of the capillary vessel….
Histology: The diagnosis of cutaneous metastasis is almost always made by the pathologist after histological review. Each tumor is unique, and the histological picture depends on the primary tumor. Treatment:…
