Extranodal NK/T-Cell Lymphoma: Nasal Type
Fig. 65.1 ENTL, nasal type: Ulcerated tumor in the nasal area (Courtesy of Dr. Alistair Robson, London, UK) Pathology ENTL is characterized by dense dermal and subcutaneous infiltrates with an…
Dermatology
Primary Cutaneous γ/δ T-Cell Lymphoma
Fig. 67.1 Subcutaneous GD-TCL: Infiltrated and ulcerated plaque on the arm (By courtesy of Dr. B. Pfeiff, Germany) Pathology CGD-TCL shows epidermotropic, dermal (diffuse or nodular), and/or subcutaneous infiltrates. The…
Blastic Plasmacytoid Dendritic Cell Neoplasm
Fig. 70.1 BPDCN: Clinical manifestation with contusiform macules on the trunk Pathology In fully developed skin lesions, there is a dense dermal monomorphous infiltrate of blasts. The infiltrate is separated…
Adult T-Cell Lymphoma/Leukemia
Fig. 63.1 ATLL, acute form: disseminated papules on both legs, nodules on the trunk and extremities (Courtesy of Dr. Dr Moussa Diallo, Dept. of Dermatology, University Hospital Dakar, Senegal) Fig….
Primary Cutaneous Extraskeletal Osteosarcoma
Fig. 45.1 PC-EO displays sheets of hyperchromatic spindle cells with an intervening network of densely eosinophilic osteoid which shows focal calcification Fig. 45.2 In addition to osteoid production, cartilaginous differentiation…
Clear Cell Sarcoma of Soft Tissue (Malignant Melanoma of Soft Tissue)
Fig. 55.1 Clear cell sarcoma of soft tissue. The neoplasm is characterized by uniform nests and fascicles separated by delicate fibrous septa of hyaline collagen Fig. 55.2 Clear cell sarcoma…
Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma
Fig. 66.1 CD8+ AECTCL: Clinical presentation with disseminated erosive plaques on the trunk (By courtesy of Dr. Dipendra Gurung, Kathmandu, Nepal) Pathology Histology shows prominent epidermotropism of mostly small to…
Cutaneous Leiomyosarcoma
Fig. 42.1 Cutaneous leiomyosarcoma. A slow-growing erythematous to brownish nodule of 5 cm in diameter on the leg The familial occurrence of cutaneous leiomyosarcoma with renal cancer has been described…
Subcutaneous Panniculitis-Like T-Cell Lymphoma
Fig. 64.1 SPTCL: Infiltrated deep-seated skin lesions on the neck with ulceration (Courtesy of Prof. Dr. G. Burg, Zürich) Pathology SPTCL is characterized by lobular infiltrates composed of small- to…
Primary Cutaneous Ewing Sarcoma/Primitive Neuroectodermal Tumor
Fig. 57.1 Primary cutaneous ES/PNET displays a nodular dermal-based proliferation of small round blue cells (Image courtesy of Steven D. Billings, MD) Fig. 57.2 ES/PNET is composed of hypercellular sheets…
