Abstract In addition to primary and secondary B- and T-cell lymphomas, there are benign lymphocytic infiltrates of the skin that can sometimes mimic cutaneous lymphomas. The latter include lymphocytic infiltrate…
Abstract Smooth muscle, adipose and cartilage neoplasms arising in the skin and subcutis comprise a wide spectrum of benign and malignant neoplasms that show myocyte, adipocyte, and chondrocyte differentiation, respectively….
Abstract Mastocytosis may occur at any age and results from mast cell proliferation, which can involve the skin, bone marrow, and other organs. Activating mutations in KIT have a pathogenic…
Abstract Cutaneous metastases are uncommon and in general are associated with a poor prognosis; rarely, they may be the presenting sign of an internal malignancy. Epidemiologic statistics are helpful in…
Abstract Skin conditions are a major cause of morbidity worldwide, representing the fourth most common source of nonfatal disease burden. Considering the high or increasing prevalence of many skin conditions,…
Abstract Benign cutaneous pigmented lesions may result from an increased production of melanin or a proliferation of melanocytes. In ephelides, café-au-lait macules (CALMs), Becker melanosis, and lentigines, there is an…
Abstract In this chapter the term neoplasm is used synonymously with tumor in a general, albeit imperfect, sense, consistent with its common usage: an abnormal proliferation (“new growth”) of cells…
Abstract Adnexal neoplasms encompass both benign and malignant tumors with differentiation towards hair follicles as well as the ducts and secretory components of sebaceous, eccrine and apocrine glands. Those tumors…
Abstract Vascular malformations result from errors in the morphogenesis of embryonic capillary, venous, arterial, and/or lymphatic channels. The clinical appearance, natural history, associated manifestations, evaluation, and therapy depend on the…
