Pediatric Graft-Versus-Host Disease
Fig. 9.1 Pathophysiology of acute GVHD. IL 1 interleukin 1, IFN γ interferon γ, LPS lipopolysaccharide, Treg regulatory T cell, Th1 T-helper cell, CTL cytotoxic T lymphocyte [2]. Reprinted from…
Fig. 9.1 Pathophysiology of acute GVHD. IL 1 interleukin 1, IFN γ interferon γ, LPS lipopolysaccharide, Treg regulatory T cell, Th1 T-helper cell, CTL cytotoxic T lymphocyte [2]. Reprinted from…
Targeted anticancer agent Cutaneous adverse effects Treatment options EGFR inhibitors – Papulopustular eruption – Xerosis – Nail changes (paronychia, pyogenic granulomas) – Hair changes ( trichomegaly, hirsutism) – TCS, oral TCNs – Emollients – TCS or topical…
Fig. 3.1 Pseudolymphomatous folliculitis. Indurated erythematous nodule with associated follicular accentuation and scale on the forehead of an adolescent A special form of CLH that is more common in children…
Syndrome Gene mutation and inheritance Clinical features RMS type and/or features Other associated malignancies Li–Fraumeni P53 AD Early onset malignancy, familial Anaplastic RMS presents in children <3 years old • Breast…
Fig. 11.1 Basal cell carcinoma on the nose of a teenage heart transplant recipient (image courtesy of Susan J. Bayliss, MD) Voriconazole , a triazole antifungal , is effective at…
Fig. 5.1 Numerous small skin-colored, dome-shaped papules on the neck, consistent with early basal cell carcinomas in Gorlin syndrome Fig. 5.2 Palmar pits , which can be subtle clinically but…
Fig. 10.1 Widespread cutaneous methicillin-sensitive Staphylococcus aureus infection in a renal transplant recipient (image courtesy of Carrie C. Coughlin, MD) Cellulitis is a superficial infection of the dermis and/or subcutaneous…
Classification Percent of pediatric cases (%) Description Associated signs and symptoms Prognosis Cutaneous solitary mastocytoma 20 Solitary macule or plaque with mast cell infiltrate Itching, lymphadenopathy Excellent: >90% show partial…
Fig. 1.1 Characteristic appearance of a Spitz nevus as a smooth dome-shaped pink papule [16]. Reprinted from Journal of the American Academy of Dermatology, Vol. 65, No. 6, Luo S,…