Renal Disease and the Skin
Abstract Chronic kidney disease (CKD) has numerous deleterious systemic effects including impaired function of the heart, brain, and nervous system, altered hormonal balance and bone metabolism, and a decreased ability…
Acquired Immunodeficiency Syndrome and Sexually Transmitted Infections
Abstract Human immunodeficiency syndrome (HIV) infection can be related to the development of a variety of skin diseases, and dermatologic diagnoses in HIV patients may be a reflection of their…
Cardiovascular Diseases and the Skin
Abstract Several systemic disorders, including inherited and inflammatory disorders, may manifest with both cardiovascular and cutaneous findings. In addition, certain cutaneous findings, such as psoriasis, a diagonal earlobe crease, and…
Fungal Diseases
Abstract Cutaneous fungal infections with systemic involvement can be divided clinically into subcutaneous mycoses and systemic mycoses, based on mode of acquisition and the extent of tissue involvement. Subcutaneous mycoses…
Protozoal Diseases
Abstract Protozoan organisms continue to represent a major disease burden worldwide. Diseases such as toxoplasmosis affect much of the population, and other diseases like leishmaniasis have undergone a resurgence in…
Bacterial and Rickettsial Diseases
Abstract Cutaneous bacterial infections are important causes of morbidity. Meticillin-resistant staphylococcal infections present as abscess or folliculitis, and drainage remains the key component of management. Lyme disease presents with annular…
Hepatic Disease and the Skin
Abstract There are numerous cutaneous manifestations of liver disease. This chapter focuses on the most common cutaneous manifestations of hepatic disease including diagnosis, management, and therapy. KeywordsCryoglobulins, Hemochromatosis, Hepatic, Hepatitis,…
Viral Diseases
Abstract Viruses produce a variety of cutaneous changes, including morbilliform (measles-like), papular, and vesicular eruptions. It is often difficult to distinguish viral exanthems from morbilliform drug eruptions; however, subtle distinguishing…
Cutaneous Diseases Associated with Gastrointestinal Abnormalities
Abstract Gastrointestinal diseases have many cutaneous associations. Gastrointestinal hemorrhage may be associated with the peau d’orange plaques of pseudoxanthoma elasticum or the macular telangiectases of hereditary hemorrhagic telangiectasia. Adenomatous polyposis…
