Overview of Hematopoietic Cell Transplantation

Oct 14, 2017 by in Dermatology Comments Off on Overview of Hematopoietic Cell Transplantation

Fig. 1.1 Increasing numbers of patients are undergoing allogeneic hematopoietic stem cell transplantation (HSCT) every year (Adapted from Pasquini and Zhu [1]; with permission) Historical Perspective Pioneering experimentation by Jacobson…

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Pediatric Graft-Versus-Host Disease

Sep 3, 2017 by in Dermatology Comments Off on Pediatric Graft-Versus-Host Disease

Host variables  Recipient age <1 or >10 years [10]  Malignancy as indication for transplant, as well as features of more advanced disease (WBC >50 × 109/L and cytogenetic abnormalities t(4;11),…

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Dermal and Subcutaneous Chronic Graft-Versus-Host Disease

Sep 3, 2017 by in Dermatology Comments Off on Dermal and Subcutaneous Chronic Graft-Versus-Host Disease

Fig. 8.1 Shiny, hypopigmented plaques with satellite plaques over the gluteal fold, representing superficial dermal chronic graft-versus-host disease (cGVHD) of the lichen sclerosus type Deep Dermis: Morpheaform Type The classic…

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Atypical Manifestations of Graft-Versus-Host Disease

Sep 3, 2017 by in Dermatology Comments Off on Atypical Manifestations of Graft-Versus-Host Disease

Common manifestations Atypical manifestations aGVHD cGVHDa aGVHD cGVHD Maculopapular rash Poikiloderma Eczematous eruptions (contact dermatitis [2], eczema craquele [3]) Eczematous eruptions [4, 5] (atopic dermatitis [6], eczema craquele [7], and…

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