Keywords Infliximab, TNF-α, Psoriasis, SPIRIT, EXPRESS, EXPRESS II, IMPACT   Key points • Infliximab is a safe and effective therapy for the treatment of moderate-to-severe psoriasis. • The mechanism of…

Keywords Cyclosporine, CsA, Neoral, Sandimmune, PISCES, PREWENT   Key points • Cyclosporine (CsA) is a highly effective treatment option for patients with moderate-to-severe plaque psoriasis with a rapid onset of…

Keywords Acitretin, Etretinate, Phototherapy, PUVA, Broadband UV-B, Narrowband UV-B, Teratogenic, Hyperlipidemia   Key points • Acitretin is an effective agent for the treatment of plaque psoriasis and is often used…

Keywords Methotrexate, MTX, Folate antagonist, CHAMPION, RESTORE1   Key points • Methotrexate (MTX) remains a safe and effective modality for the treatment of severe, recalcitrant psoriasis when used appropriately. •…

Keywords Psoralen-UV-A, PUVA, Photochemotherapy, Psoriasis   Key points • Psoralen-UV-A (PUVA) photochemotherapy involves use of either an oral or topical psoralen followed by exposure to long-wave UV-A radiation. This combination…

Keywords Psoriasis, Plaque psoriasis, Clinical subtypes, Pustular psoriasis, Nail psoriasis, Comorbidities   Key points • Today, psoriasis is a global disease causing significant impairment in quality of life, disfiguring morbidity,…