Antiviral Population Route Age/weight Dosing Acyclovira,b Eczema herpeticum PO All ages 15 mg/kg/day (400 mg maximum) in 3–5 divided doses for 10–14 days or until all mucocutaneous lesions are healed…

Fig. 14.1 Impetigo. Superficial erosions on the cheeks of an adolescent male Fig. 14.2 Impetigo. Erosions with superficial desquamation on the neck Fig. 14.3 Ecthyma. Punched-out ulcer with purulent exudate…

Fig. 3.1 Typical erythematous crusted and excoriated plaques with lichenification in two children with atopic dermatitis Fig. 3.2 Typical erythematous crusted and excoriated plaques with lichenification in two children with…

Fig. 9.1 Varying clinical appearances of congenital melanocytic nevi. (a) A medium-sized, evenly pigmented congenital melanocytic nevus on the arm. (b) A large heterogeneous congenital melanocytic nevus on the scalp…

Fig. 4.1 Plaque psoriasis on the torso. Note the Koebnerization along the patient’s surgical scar Fig. 4.2 Guttate psoriasis Fig. 4.3 Diaper psoriasis. Note the psoriatic lesions outside the diaper…

Clinical criteria Vascular thrombosis  Venous or arterial thrombosis may be present  Thrombosis must be confirmed by imaging studies or by histopathology Laboratory criteriaa 1. Anti-cardiolipin antibody 2. Anti-β2 glycoprotein-1 antibody…

Fig. 24.1 A baby with failure to thrive and poor wound healing after delayed separation of umbilical stump Fig. 24.2 Treatment-resistant thrush in undifferentiated immunodeficiency disorder Table 24.1 Clinical cutaneous…

Trichorrhexis invaginata Microscopic examination of hair shaft: bamboo hair. Hair shaft with multiple knots resembling the ball-and-cup joint of bamboo Dermoscopy: nodular swellings at irregular intervals, ball-shaped knots similar to…

Inherited ichthyoses Non-syndromic Mode of inheritance Genes Common ichthyoses Ichthyosis vulgaris Autosomal semi dominant FLG Autosomal recessive congenital ichthyosis Harlequin ichthyosis Autosomal recessive ABCA12 Lamellar ichthyosis Autosomal recessive TGM1/NIPAL4/ALOX12B/ABCA12 Congenital…

For diagnosis  Clinical evaluation  Biopsy rarely needed for confirmation  Genetic screen for mucopolysaccharidoses in extensive cases For treatment  Tincture of time—most lesions resolve by age 6 years The most common…