Pipeline Therapeutics
Introduction Since early 2000, there has been a dramatic increase in the number of publications and clinical trials devoted to moderate to severe hidradenitis suppurativa (HS). HS is a complex…
Introduction Since early 2000, there has been a dramatic increase in the number of publications and clinical trials devoted to moderate to severe hidradenitis suppurativa (HS). HS is a complex…
Introduction Hidradenitis suppurativa/acne inversa (HS) is a chronic, inflammatory, recurrent, debilitating skin disease of the hair follicle which affects apocrine gland-rich areas of the body. The disease usually presents after…
Introduction Hidradenitis suppurativa (HS) poses many challenges to patients, including delays in diagnosis, recurring pain, discomfort, and inadequate symptom coverage with conventional therapies. A survey study of 303 HS patients…
Introduction In the last few decades, surgical interventions for hidradenitis suppurativa (HS) have expanded well beyond traditional excisional approaches with the popularization of deroofing, the use of electrosurgical and laser-based…
Introduction Pain is the most burdensome symptom of hidradenitis suppurativa (HS), accounting for greater impairment in HS-related quality of life (QoL) than even disease severity. Although it has received relatively…
Introduction Hidradenitis suppurativa (HS) is characterized by relapsing, painful, suppurating, bleeding nodules, abscesses, and sinus tracts that primarily affect intertriginous skin. Aside from its debilitating physical manifestations, the disease carries…
Introduction to Wound Care in Hidradenitis Suppurativa The most important step in managing hidradenitis suppurativa (HS)-related wounds is to treat the underlying disease with appropriate medical and surgical approaches. Even…
Introduction The pathogenesis of hidradenitis suppurativa (HS) remains to be fully elucidated. Genetic susceptibility along with hormonal fluctuations and immune dysregulation are all thought to contribute to HS development. HS…
Introduction Hidradenitis suppurativa (HS) is a chronic inflammatory disorder with a complex, multifactorial, and incompletely elucidated pathophysiology. Among relevant host factors are a number of important inflammatory pathways, including increased…
Introduction Antibiotics alone, or in combination with other therapeutic strategies, have been empirically used in hidradenitis suppurativa (HS) with variable success, resulting only in temporary symptom relief in the disease…