6 Preservation and perfusion of abdominal organs for transplantation John O’Callaghan, Peter Friend and Rutger J. Ploeg Introduction Why is organ preservation necessary? At the dawn of clinical transplantation, organ…
12 Transplant infectious disease Camille Nelson Kotton Introduction and general concepts Immunosuppression makes organ transplantation possible, while increasing the risk of infections, both routine and opportunistic. Understanding how to optimally…
11 Cardiothoracic transplantation Asif Hasan and John H. Dark Introduction The first successful heart transplantation undertaken on December 1967, at least in the public eye, represents a defining moment in…
8 Liver transplantation James J. Pomposelli, Mary Ann Simpson, Caroline J. Simon and Elizabeth A. Pomfret Introduction Liver transplantation has evolved over the past six decades from a risky procedure…
3 Immunology of graft rejection George Tse and Lorna Marson Introduction The study of transplantation has played a pivotal role in defining fundamental immunological phenomena, which in turn have provided…
7 Recent trends in kidney transplantation Gabriel C. Oniscu Introduction The remarkable progress of kidney transplantation over the past five decades has been brought about by surgical refinements, developments in…
10 Islet transplantation John J. Casey Introduction The discovery of insulin by Banting and Best in the early part of the 20th century saw type I diabetes become a treatable…
5 Immunosuppression with the kidney as paradigm David Wojciechowski, Gregory Veillette and Flavio Vincenti Introduction Unless a transplant is performed between identical twins, recipients of kidney transplants generally require lifelong…
4 Testing for histocompatibility Phil Dyer, Ann-Margaret Little and David Turner Introduction Immunity The immune system exists to protect an individual from morbidity and mortality following pathogen infection and from…
13 Chronic transplant dysfunction Shikha Mehta and Roslyn B. Mannon Introduction Solid-organ transplantation provides life-saving and rejuvenating therapy for those with end-organ damage. Initial functional success is at an all-time…
