Fig. 9.1 Varying clinical appearances of congenital melanocytic nevi. (a) A medium-sized, evenly pigmented congenital melanocytic nevus on the arm. (b) A large heterogeneous congenital melanocytic nevus on the scalp…
Fig. 4.1 Plaque psoriasis on the torso. Note the Koebnerization along the patient’s surgical scar Fig. 4.2 Guttate psoriasis Fig. 4.3 Diaper psoriasis. Note the psoriatic lesions outside the diaper…
Clinical criteria Vascular thrombosis Venous or arterial thrombosis may be present Thrombosis must be confirmed by imaging studies or by histopathology Laboratory criteriaa 1. Anti-cardiolipin antibody 2. Anti-β2 glycoprotein-1 antibody…
Fig. 24.1 A baby with failure to thrive and poor wound healing after delayed separation of umbilical stump Fig. 24.2 Treatment-resistant thrush in undifferentiated immunodeficiency disorder Table 24.1 Clinical cutaneous…
Trichorrhexis invaginata Microscopic examination of hair shaft: bamboo hair. Hair shaft with multiple knots resembling the ball-and-cup joint of bamboo Dermoscopy: nodular swellings at irregular intervals, ball-shaped knots similar to…
Inherited ichthyoses Non-syndromic Mode of inheritance Genes Common ichthyoses Ichthyosis vulgaris Autosomal semi dominant FLG Autosomal recessive congenital ichthyosis Harlequin ichthyosis Autosomal recessive ABCA12 Lamellar ichthyosis Autosomal recessive TGM1/NIPAL4/ALOX12B/ABCA12 Congenital…
For diagnosis Clinical evaluation Biopsy rarely needed for confirmation Genetic screen for mucopolysaccharidoses in extensive cases For treatment Tincture of time—most lesions resolve by age 6 years The most common…
Fig. 16.1 Tinea corporis. Erythematous plaque with elevated border Fig. 16.2 Majocchi’s granuloma. Folliculocentric papules and pustules within a thin plaque with an expanding, elevated border on the cheek of…
Fig. 6.1 Ehlers-Danlos syndrome. Increased skin laxity Fig. 6.2 Ehlers-Danlos syndrome. Widened fish-mouth scar with atrophic skin on the leg The clinical features of vascular EDS can be very subtle,…
Fig. 23.1 Alternating bands of light and dark color along hair fibers indicative of periods of protein deficiency in phenylketonuria (Courtesy of Dr. Maureen Rogers) Specific Investigations Newborn screening (tandem…
