Eosinophil-Associated Dermatoses
Abstract The eosinophil circulates as a mature cell in the blood and infiltrates tissue in response to certain signals. Eosinophils are found in various inflammatory and neoplastic dermatoses, including the…
Purpura: Mechanisms and Differential Diagnosis
Abstract Purpura is a sign of several different processes including trauma, thrombocytopenia, anticoagulant use, cutaneous small vessel vasculitis, septic emboli and vascular coagulopathies, and is due to cutaneous hemorrhage. The…
Erythema Multiforme, Stevens–Johnson Syndrome, and Toxic Epidermal Necrolysis
Abstract Until recently, the nosology of severe acute bullous disorders due to infectious agents or drugs has been confusing. It has now become clear that Stevens–Johnson syndrome (SJS) and toxic…
Urticaria and Angioedema
Abstract Urticaria is characterized by transient skin or mucosal swellings due to plasma leakage. When the swelling is superficial within the dermis, pruritic wheals appear, whereas when deep, angioedema is…
Figurate Erythemas
Abstract While there are multiple cutaneous disorders that can present with annular lesions, from urticaria to granuloma annulare, this chapter focuses on the four classic figurate erythemas – erythema annulare…
Allergic Contact Dermatitis
Abstract Allergic contact dermatitis (ACD) is caused by a delayed hypersensitivity reaction within the skin, manifesting as a pruritic dermatitis initially at the site of skin contact with the allergen….
Atopic Dermatitis
Abstract Atopic dermatitis is a common inflammatory skin condition that affects up to 20–30% of children and 2–10% of adults. It represents a complex genetic disease with environmental influences and…
Basic Principles of Dermatology
Abstract All students of dermatology need a basic foundation and framework upon which to accumulate knowledge. In this chapter, the basic tenets of disease classification in dermatology are introduced. This…
Other Eczematous Eruptions
Abstract In addition to contact and atopic dermatitis, there exists a heterogeneous group of inflammatory skin diseases that obviously share the hallmarks of eczema, but also display characteristic additional features….
