Melanoma and Spitz Nevi in Children
Fig. 1.1 Characteristic appearance of a Spitz nevus as a smooth dome-shaped pink papule [16]. Reprinted from Journal of the American Academy of Dermatology, Vol. 65, No. 6, Luo S,…
Other Proliferative Disorders of the Skin
Classification Percent of pediatric cases (%) Description Associated signs and symptoms Prognosis Cutaneous solitary mastocytoma 20 Solitary macule or plaque with mast cell infiltrate Itching, lymphadenopathy Excellent: >90% show partial…
Clinical Manifestation: Adult-Type Atopic Dermatitis
Fig. 17.1 Intractable erythema of the face: erythema of the face is a common manifestation in adult (adolescence/adulthood) phase. It is characterized by edematous erythema and many papules and is…
The Role of Sweat in the Pathogenesis of Atopic Dermatitis
Fig. 11.1 Differential localization of sweat pores of eccrine glands in relation to skin folds and ridges. (a) In glabrous skin, such as fingertips, sweat pores open at the ridges…
Evolution of Animal Models of Atopic Dermatitis
Fig. 14.1 Pathomechanisms of atopic dermatitis. Environmental allergens trigger the overproduction of IgE antibody when they come in through barrier-disrupted sensitive, atopic skin, while chemical or bacterial factors induce epidermal…
Infantile and Childhood AD
Major features • Pruritus • Facial and extensor eczema in infants and children • Flexural eczema in adolescents • Chronic or relapsing dermatitis • Personal or history of atopic disease…
Differential Diagnosis of Atopic Dermatitis
Differential points Infantile eczema Childhood atopic dermatitis Adult atopic dermatitis Synonymous Infantile seborrheic dermatitis Prurigo Besnier Infantile xerotic eczema Atopic diathesis Unknown Yes Unknown Clinical manifestations Localized to the scalp…
Senile Atopic Dermatitis
Clinical type Three types have been categorized: IgE-allergic type, non-IgE-allergic type. and indeterminate-allergic type [8, 12] Skin manifestations Basically match those of adolescent/adult AD: Chronic eczema on the face and…
Epidemiology of Atopic Dermatitis in Japan
Fig. 2.1 The global AD prevalence is based on the international study of asthma and allergies in childhood (ISAAC) phase I [4] Fig. 2.2 Changes in AD prevalence at age…
Etiopathology of Atopic Dermatitis: Immunological Aspects of Dendritic Cells (DCs) and Innate Lymphoid Cells (ILCs)
Fig. 8.1 Description of skin immune cells. LCs Langerhans cells, T RM resident memory T cells, dermal DCs dermal dendritic cells, ILCs innate lymphoid cells, γδT cells gamma delta T…
