Errors in Metabolism
This chapter provides images of a collection of conditions that result from errors in metabolism. Many of these diseases manifest in the skin secondary to the deposition of material such…
Chronic Blistering Dermatoses
Immunobullous dermatoses may present with urticarial lesions, blisters, erosions, or pustules. IgA-mediated disease is characterized by annular lesions with a “string of pearls” morphology—bullous in the case of linear IgA…
Disturbances of Pigmentation
Pigmentary disorders of the skin may present with depigmentation, hypopigmentation, or hyperpigmentation. The color, morphology, and distribution of the lesions help to suggest the correct diagnosis. Vitiligo may be segmental…
Parasitic Infestations, Stings, and Bites
Bites and infestations present with wide-ranging manifestations, including papules, vesicles, excoriations, and urticarial lesions. Bedbug bites often involve the arms and develop clinical features of prurigo nodularis. A biopsy will…
Diseases Resulting From Fungi and Yeasts
Fungi and yeasts can cause both superficial and deep infections in the skin with a great variation in clinical findings. In healthy hosts, commensal organisms such as candida remain superficial,…
Endocrine Diseases
Endocrine disorders present with a range of findings that may affect any layer of the skin. The associated skin changes can lead the astute physician to suspect the underlying disorder…
Abnormalities of Dermal Fibrous and Elastic Tissue
This chapter includes a variety of conditions, all resulting from either inherited or acquired changes in the collagen or elastic tissue of the skin. Some inherited syndromes with particularly unique…
Bacterial Infections
Bacterial infections create a multitude of skin lesions, from pustules, to necrotic nodules, to ulcers. These infections range from the superficial crusted erosions of impetigo to the systemic purpuric plaques…
Lichen Planus and Related Conditions
Lichen planus (LP) and other lichenoid eruptions tend to create characteristic primary lesions and patterns. The pruritic, purple, polygonal, flat-topped papules of LP can appear unmistakably shiny as they reflect…
Contact Dermatitis and Drug Eruptions
Contact dermatitis and cutaneous drug eruptions are both skin conditions triggered by external agents that are either in direct contact with the skin or ingested. Contact dermatitis shares many features…
