Skin Cancer and Other Late Effects of Cancer Therapy
Fig. 11.1 Basal cell carcinoma on the nose of a teenage heart transplant recipient (image courtesy of Susan J. Bayliss, MD) Voriconazole , a triazole antifungal , is effective at…
Dermatology
Malignancy-Associated Genodermatoses
Fig. 5.1 Numerous small skin-colored, dome-shaped papules on the neck, consistent with early basal cell carcinomas in Gorlin syndrome Fig. 5.2 Palmar pits , which can be subtle clinically but…
Opportunistic Skin Infections in Immunosuppressed Children
Fig. 10.1 Widespread cutaneous methicillin-sensitive Staphylococcus aureus infection in a renal transplant recipient (image courtesy of Carrie C. Coughlin, MD) Cellulitis is a superficial infection of the dermis and/or subcutaneous…
Other Proliferative Disorders of the Skin
Classification Percent of pediatric cases (%) Description Associated signs and symptoms Prognosis Cutaneous solitary mastocytoma 20 Solitary macule or plaque with mast cell infiltrate Itching, lymphadenopathy Excellent: >90% show partial…
Melanoma and Spitz Nevi in Children
Fig. 1.1 Characteristic appearance of a Spitz nevus as a smooth dome-shaped pink papule [16]. Reprinted from Journal of the American Academy of Dermatology, Vol. 65, No. 6, Luo S,…
The Role of Sweat in the Pathogenesis of Atopic Dermatitis
Fig. 11.1 Differential localization of sweat pores of eccrine glands in relation to skin folds and ridges. (a) In glabrous skin, such as fingertips, sweat pores open at the ridges…
Clinical Manifestation: Adult-Type Atopic Dermatitis
Fig. 17.1 Intractable erythema of the face: erythema of the face is a common manifestation in adult (adolescence/adulthood) phase. It is characterized by edematous erythema and many papules and is…
Infantile and Childhood AD
Major features • Pruritus • Facial and extensor eczema in infants and children • Flexural eczema in adolescents • Chronic or relapsing dermatitis • Personal or history of atopic disease…
Evolution of Animal Models of Atopic Dermatitis
Fig. 14.1 Pathomechanisms of atopic dermatitis. Environmental allergens trigger the overproduction of IgE antibody when they come in through barrier-disrupted sensitive, atopic skin, while chemical or bacterial factors induce epidermal…
Differential Diagnosis of Atopic Dermatitis
Differential points Infantile eczema Childhood atopic dermatitis Adult atopic dermatitis Synonymous Infantile seborrheic dermatitis Prurigo Besnier Infantile xerotic eczema Atopic diathesis Unknown Yes Unknown Clinical manifestations Localized to the scalp…
