Hansen Disease
Clinical manifestations of leprosy vary from the subtle hypopigmented patches of indeterminate leprosy to the diffuse facial infiltration and nodules of lepromatous leprosy. The clinical and histologic manifestations of the…
Pityriasis Rosea, Pityriasis Rubra Pilaris, and Other Papulosquamous and Hyperkeratotic Diseases
Pityriasis rosea presents with erythematous macules that develop a delicate central silver scale. As the lesions evolve, they assume an oval configuration often best observed on the back and flanks….
Mycobacterial Diseases
Tuberculosis and atypical mycobacterial infections can be difficult to diagnose clinically and require a high index of suspicion and familiarity with their manifestations in the skin. Tuberculosis (TB) is more…
Atopic Dermatitis, Eczema, and Noninfectious Immunodeficiency Disorders
Dermatitis can present with a variety of physical examination findings ranging from exuberant oozing to dry scale. These findings represent the acute and chronic inflammation that defines a variety of…
Dermatoses Resulting from Physical Factors
This chapter catalogues many examples of how the skin reacts to the external environment from which it protects the body. Exposure to physical factors such as heat, cold, moisture, ultraviolet…
Pruritus and Neurocutaneous Diseases
Pruritus often produces distinctive skin lesions, characterized by angulated borders. Endogenous diseases (in common parlance, an “inside job”) tend to produce lesions that are rounded in character, whereas exogenous caustic…
Cutaneous Signs and Diagnosis
The astute clinician uses the appearance of the eruption and its accompanying symptoms to arrive at an accurate diagnosis. A symptom, such as itch or pain, is something that the…
Structure and Function
The diagnosis of skin disease is based on color, morphology, and distribution of cutaneous lesions. The structure of the skin and associated appendages relates directly to these characteristics. Folliculitis presents…
