Scars and Stress
Fig. 7.1 Ear keloid in an Afro-American patient In this chapter we aim to show evidence that stress can affect wound healing producing unaesthetic scars, such as keloids, and suggest…
Itch and Stress
Category Examples of diseases I – Dermatological Atopic dermatitis, urticaria, eczematous disorders, psoriasis, scabies II – Systemic Chronic kidney disease, primary biliary cirrhosis, Hodgkin’s disease, drug-induced itch III – Neurological…
Clinical Presentation of Nonsclerotic Epidermal Chronic Graft-Versus-Host Disease and Hair and Nail Changes
Organ or site Diagnostic (sufficient to establish the diagnosis of chronic GVHD) Distinctive (seen in chronic GVHD, but insufficient alone to establish a diagnosis) Other features or unclassified entities Skin…
Clinical Presentation of Acute Cutaneous Graft-Versus-Host Disease
Fig. 3.1 Erythema of the face with accentuation of the ear Fig. 3.2 Erythema of the ear Fig. 3.3 Palmar erythema Fig. 3.4 Palmar erythema (Note microvesicles that herald edema.)…
Pediatric Graft-Versus-Host Disease
Host variables Recipient age <1 or >10 years [10] Malignancy as indication for transplant, as well as features of more advanced disease (WBC >50 × 109/L and cytogenetic abnormalities t(4;11),…
Dermal and Subcutaneous Chronic Graft-Versus-Host Disease
Fig. 8.1 Shiny, hypopigmented plaques with satellite plaques over the gluteal fold, representing superficial dermal chronic graft-versus-host disease (cGVHD) of the lichen sclerosus type Deep Dermis: Morpheaform Type The classic…
Atypical Manifestations of Graft-Versus-Host Disease
Common manifestations Atypical manifestations aGVHD cGVHDa aGVHD cGVHD Maculopapular rash Poikiloderma Eczematous eruptions (contact dermatitis [2], eczema craquele [3]) Eczematous eruptions [4, 5] (atopic dermatitis [6], eczema craquele [7], and…
Histopathology of Cutaneous Graft-Versus-Host Disease
Lerner grading system [11] Horn grading system [7] Grade 0 Normal skin or unrelated cutaneous disease Grade 1 Vacuolar alteration Vacuolar alteration Grade 2 Spongiosis and dyskeratosis (eosinophilic bodies)…
Diagnosis, Staging, and Treatment of Chronic Graft-Versus-Host Disease
Fig. 10.1 Poikilodermic cGVHD on the neck and upper chest Fig. 10.2 Lichen planus–like chronic graft-versus-host disease (cGVHD). (a) Woman with lichen planus–like cGVHD on the face. (b) Man with…
Wound Care in the Management of Chronic Graft-Versus-Host Disease
Fig. 11.1 Cleansing daily with soap and warm water should be encouraged for patients with sclerotic chronic GVHD. Before (a) and after (b); 2 days of soap and water cleansing…
