Abstract Neutrophilic dermatoses comprise a spectrum of skin diseases with various cutaneous manifestations and a predominantly neutrophilic infiltrate on histopathology. Neutrophilic dermatoses are associated with a variety of systemic diseases…
Abstract Autoinflammatory syndromes are a recently described group of disorders characterized by inflammation mediated by the innate immune system. All these syndromes have cutaneous presentations in addition to multiorgan involvement….
Abstract Cutaneous findings are commonly observed in rheumatologic conditions. These skin findings occur in association with underlying rheumatologic disease and are variably associated with disease state activity. In this chapter…
Abstract The clinical differential diagnosis of “hard skin” can be divided into two main diagnostic categories: morphea and morphea-like conditions and systemic sclerosis and sclerodermoid conditions. Patients with morphea and…
Abstract Vasculitis includes a heterogeneous group of conditions characterized by blood vessel inflammation and necrosis. The clinical manifestations depend on the localization and size of the involved vessel. Most patients…
Abstract Psoriasis is an immune-mediated chronic skin disease that affects about 125 million patients worldwide. About one-third of patients may also develop psoriatic arthritis. Patients with psoriasis are at increased…
Key Points • Lupus erythematosus is a multisystem disorder that frequently has cutaneous involvement • Lupus-specific skin disease can be characterized as acute, subacute, or chronic based on clinical and…
Abstract Dermatomyositis is a condition that combines an inflammatory myopathy with a characteristic cutaneous disease. Its pathogenesis is only partially understood, but immune-mediated muscle damage is believed to be important…
