Clinical type Three types have been categorized: IgE-allergic type, non-IgE-allergic type. and indeterminate-allergic type [8, 12] Skin manifestations Basically match those of adolescent/adult AD: Chronic eczema on the face and…
Fig. 2.1 The global AD prevalence is based on the international study of asthma and allergies in childhood (ISAAC) phase I [4] Fig. 2.2 Changes in AD prevalence at age…
Fig. 8.1 Description of skin immune cells. LCs Langerhans cells, T RM resident memory T cells, dermal DCs dermal dendritic cells, ILCs innate lymphoid cells, γδT cells gamma delta T…
Definition Atopic dermatitis is a pruritic, eczematous dermatitis; its symptoms chronically fluctuate with remissions and relapses. Most individuals with atopic dermatitis have atopic diathesis Atopic diathesis: (1) personal or family…
AD AR BA FA Number of patients 3068 4933 2060 1787 No complications 1320 (43.0%) 2976 (60.3%) 784 (38.1%) 623 (34.9%) Complication AD – 1174 (23.8%) 675 (32.8%) 714…
Fig. 26.1 Partial cellular and molecular immunological mechanisms in lesional skin of AD. Factors surrounded by red square are targets of therapeutic approaches described in this manuscript. ‘Acute’ shows acute…
Fig. 24.1 Causes and exacerbating factors. Since causes and exacerbating factors vary among patients, care should be taken to identify them sufficiently for each patient before taking removal measures. Modified…
Diagnostic term Author Mycosis sive eczema flexurarum Hebra (1884) Lichen simplex chronicus disseminatus Vidal (1886) Neurodermite disseminatus Brocq and Jacquet (1891) Prurigo diathetique eczemato-lichenienne Besnier (1892) Neurodermite diffuse Brocq (1902)…
Fig. 25.1 Conceptual illustration of “absenteeism” and “presenteeism” There are several assessment procedures for measuring patients’ work productivity. Those procedures share core assessment domains with each other. The major shared…
Fig. 23.1 Proportions of infants who did not have AD/eczema. Kaplan-Meier plots show the proportions of infants in the intervention (circle) and control (triangle) groups with AD/eczema during the first…
