Systemic Therapy for Cutaneous Melanoma
This article provides a review of the current medical management of patients with high-risk and metastatic cutaneous melanoma, including a review of the use of adjuvant interferon therapy and a…
Complete Lymph Node Dissection for Regional Nodal Metastasis
The primary management of lymph nodes involved with metastatic melanoma is regional lymphadenectomy. Axillary or inguinal node complete lymph node dissection (CLND) is performed after an occult metastasis is found…
Evaluation of Sentinel Lymph Nodes for Melanoma Metastases by Pathologists
The pathologic evaluation of sentinel lymph nodes for melanoma metastases is not without significant challenges. It is affected by significant variation in approaches, which may compromise the final interpretation, leading…
The Role of Lymphatic Mapping and Sentinel Lymph Node Biopsy in the Staging and Treatment of Melanoma
The incidence of malignant melanoma is increasing at an alarming rate, doubling in women and growing by more 300% in men during the past 25 years. The importance of diagnosing…
Head and Neck Melanoma
Nearly 20% of malignant melanoma in the human body occurs in the head and neck. Most studies divide the sites of origin of malignant melanoma in the head and neck…
Surgical Management of Primary Disease
Despite advancements in the treatment of melanoma, surgical management remains the cornerstone for treatment and long-term survival. The authors present their surgical approach to the patient with melanoma including evaluation,…
Melanoma: Workup and Surveillance
There is no clear consensus on the best means of detecting melanoma, particularly recurrence of melanoma. Physical examination remains paramount, but other means have been recommended also. This article provides…
Epidemiology, Staging (New System), and Prognosis of Cutaneous Melanoma
Melanoma remains one of the most deadly of skin cancers and its incidence has been rising steadily throughout the past several decades. The risk factors associated with melanoma include external…
Lentigo Maligna: Diagnosis and Treatment
Lentigo maligna is an overgrowth of atypical melanocytes at the dermal–epidermal junction also known as melanoma in situ. Left untreated, these lesions can continue to grow, resulting in dermal invasion…
The Spitz Nevus: Review and Update
The Spitz nevus is a relatively common skin lesion in children and is less commonly seen in adults. The lesion is defined by the presence of distinctive-appearing spindle or epithelioid…
