The Genetics of Hidradenitis Suppurativa
A family history of hidradenitis suppurativa (HS) is reported by about one-third of patients, and the pattern of inheritance suggests a single gene disorder inherited as an autosomal dominant trait….
The Handicap of Hidradenitis Suppurativa
Hidradenitis suppurativa (HS) is a chronic skin disease, with painful, foul-smelling, recurring inflammation, leading to a diminished quality of life. Patients with HS also often suffer from depression, have an…
Diagnosing Hidradenitis Suppurativa
Three diagnostic criteria must be met for hidradenitis suppurativa: typical lesions, occurrence in one or more of the predilection areas, and that it is chronic and/or recurrent. Several outcome measures…
Prevalence, Risk Factors, and Comorbidities of Hidradenitis Suppurativa
It is challenging to estimate a true prevalence of hidradenitis suppurativa (HS) because it is underdiagnosed and misdiagnosed. Prevalences have been reported from 0.00033% to 4.1%. The incidence seems to…
The Secret Scourge
Gregor B.E. Jemec, MD, DMSc, Editor Some diseases have a greater impact than others. Hidradenitis suppurativa (HS) is a high-impact disease, not only due to its signs and symptoms but…
BRAF Mutations in Erdheim-Chester Disease
Erdheim-Chester disease (ECD) is a xanthogranulomatous disease with variable manifestations that can also severely involve the orbit. In their recent article, “Adult orbital xanthogranulomatous disease: a review with emphasis on…
When Acne is Not Acne
Acne vulgaris (AV) is considered a straightforward diagnosis made clinically without specific diagnostic testing. However, certain disorders may simulate AV, such as multiple small epidermal cysts or deep milia, multiple…
Physical Modalities (Devices) in the Management of Acne
Treatment options for acne vulgaris are enhanced by laser and light therapy. Both visible and laser light are effective treatments for acne. Visible light and many lasers target Propionibacterium acnes…
Evaluation of Acne Scars
The prevalence and emotional impact of acne scarring are underestimated by the medical community. Dermatology providers should be able to evaluate the acne scar patient and discuss treatment options. Important…
Evaluation and Management of Refractory Acne Vulgaris in Adolescent and Adult Men
Acne vulgaris alters the normal skin physiology, impairing stratum corneum and transepidermal water loss. A male’s normal skin physiologic state is different than a female’s and may have implications when…
