Country Year of endorsement National guideline or recommendation (title in English) References Australia 2000, 2006 Note for Guidance on Good Clinical Practice (CPMP/ICH/135/95) The Australian Clinical Trial Handbook, 2006 Therapeutic…
© Springer-Verlag Berlin Heidelberg 2017Nina Dragicevic and Howard I. Maibach (eds.)Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin10.1007/978-3-662-53270-6_22 22. Active Enhancement Methods in Transdermal Drug Delivery: Current Status and Future Perspectives Ryan F. Donnelly1 (1) School of…
© Springer-Verlag Berlin Heidelberg 2017Nina Dragicevic and Howard I. Maibach (eds.)Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin10.1007/978-3-662-53270-6_21 21. Perspectives on Dermal Delivery of Macromolecular Drugs Marianna Foldvari1 and P. Kumar2 (1) School of Pharmacy, University of…
S. No Enhancement method Technology Manufacturer Drug 1 Iontophoresis E-Trans® Alza Fentanyl 2 Iontophoresis Iontophoretic drug delivery system Iomed® Lidocaine and epinephrine 3 Microporation Microstructured transdermal system 3 M Hydrophilic…
© Springer-Verlag Berlin Heidelberg 2017Nina Dragicevic and Howard I. Maibach (eds.)Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin10.1007/978-3-662-53270-6_18 18. Retardation Strategies for Sunscreen Agents Katharina Bohnenblust-Woertz1 and Christian Surber2, 3 (1) Galderma Spirig, Egerkingen, Switzerland (2) University…
Fig. 17.1 Corneoxenometry. Aspect of a cyanoacrylate skin surface stripping stained by a toluidine blue-basic fuchsine after contact with a penetration enhancer. The staining of corneocytes is uneven and indicates…
Fig. 14.1 ATR-FTIR spectrum of porcine ear skin recorded at 32 °C, showing the typical skin bands Although it represents a very basic and simplified model of the human skin…
Fig. 8.1 Breadloaf technique. (a) Standard excision processed with breadloaf technique (Image ©2016, Memorial Sloan Kettering Cancer Center. Used with permission). (b) Melanoma excised with standard margin as an ellipse….
Fig. 16.1 Biopsy proven lentigo maligna melanoma with ill-defined clinical borders Fig. 16.2 Wood’s light examination of pigmented lesion Fig. 16.3 Dermoscopic examination of pigmented lesion Fig. 16.4 Reflectance confocal…
Study Recurrence rate 95 % CI % weight Lower Upper Excision Pitman [34] 0.09 0.01 0.29 2.31 Hill [35] 0.02 0 0.08 3.05 Argawal-Antal [36] 0 0 0.04 3.2 Osborne…
