Role of Interleukin 1 in Atopic Dermatitis
Interleukin-1 (IL-1) is a potent inflammatory cytokine that plays a central role in the innate immune response. IL-1 mediates the acute phase of inflammation by inducing local and systemic responses,…
Psoriasis as Autoinflammatory Disease
This article presents a summary of the evidence for a link between autoinflammatory diseases and psoriasis. The main concepts regarding the disease state of psoriasis are discussed and these lead…
What Do Autoinflammatory Syndromes Teach About Common Cutaneous Diseases Such as Pyoderma Gangrenosum? A Commentary
Pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterized by ulcerating skin lesions with rapid onset and recalcitrant treatment course. PG treatment targets an array of inflammatory pathways with variable success….
Autoinflammatory Pustular Neutrophilic Diseases
This article provides a new categorization of inflammatory pustular dermatoses in the context of recent genetic and biological insights. Monogenic diseases with pustular phenotypes are discussed, including deficiency of interleukin…
Autoinflammatory Diseases in Dermatology
Autoinflammatory diseases, including CAPS, TRAPS, HIDS, FMF, Blau, and CANDLE, have unique dermatologic presentations that can be a clue to diagnosis. Although these conditions are rare, the morbidity and mortality…
Introduction to Autoinflammatory Syndromes and Diseases
Autoinflammatory syndromes and diseases are a group of disorders of innate immunity. This group has grown rapidly in recent years as a result of research advancements in molecular biology and…
Autoinflammatory Diseases and Syndromes in Dermatology
William Abramovits, MD, Editor Marcial Oquendo, MD, Editor Medical Dermatologists, assuming that they are all like me, and I am like them, take diagnostic and therapeutic challenges as fun and…
Hair Shafts in Trichoscopy
Trichoscopy (hair and scalp dermoscopy) analyzes the structure and size of growing hair shafts, providing diagnostic clues for inherited and acquired causes of hair loss. Types of hair shaft abnormalities…
Dermoscopy in General Dermatology
In addition to its traditional use for the evaluation of skin tumors, dermoscopy continuously gains appreciation in other fields of dermatology. The patterns of several inflammatory and infectious skin diseases…
Pink Lesions
Dermoscopy (dermatoscopy or surface microscopy) is an ancillary dermatologic tool that in experienced hands can improve the accuracy of diagnosis of a variety of benign and malignant pigmented skin tumors….
