Cutaneous Manifestations of B-cell Chronic Lymphocytic Leukemia B-cell chronic lymphocytic leukemia (B-CLL) represents the most frequent type of chronic lymphocytic leukemia [1]. In patients affected by the disease cutaneous lesions…
Subcutaneous Panniculitis-like T-cell Lymphoma Subcutaneous panniculitis-like T-cell lymphoma is included as a distinct entity in the World Health Organization (WHO) Classification of Tumours of Haematopoietic and Lymphoid Tissues [1]. As…
Intravascular Large Cell Lymphomas It is yet unclear whether the two phenotypic variants of intravascular large cell lymphoma, namely, the more frequent B-cell type and the exceedingly rare natural killer…
Cutaneous Peripheral T-Cell Lymphoma, not Otherwise Specified (NOS) Cutaneous peripheral T-cell lymphoma, not otherwise specified (NOS) represents a “waste basket” of all cases that cannot be put into another of…
Cutaneous CD4+ small–medium T-cell Lymphoma Cutaneous CD4+ small–medium T-cell lymphoma is listed as a provisional entity in the World Health Organization (WHO) Classification of Tumours of Haematopoietic and Lymphoid Tissues…
Cutaneous Manifestations of Hodgkin Lymphoma Hodgkin lymphoma is a distinct malignant lymphoma characterized by the presence of neoplastic Reed–Sternberg cells in association with different patterns of reactive cells. In the…
Other Cutaneous NK/T-Cell Lymphomas Besides the entities discussed in the previous chapters, several other types of natural killer (NK)/T-cell lymphoma have been described at cutaneous sites, including cases arising both…
Sézary Syndrome Sézary syndrome is characterized clinically by pruritic erythroderma, generalized lymphadenopathy, and the presence of circulating malignant T lymphocytes (Sézary cells). Other typical cutaneous changes include palmoplantar hyperkeratosis, alopecia,…
Cutaneous Manifestations of Other Leukemias Besides B-cell chronic lymphocytic leukemia (B-CLL) and myelogenous leukemias, the skin may be the site of specific manifestations in other types of leukemia. In most…
Cutaneous Adult T-Cell Leukemia/Lymphoma Adult T-cell leukemia/lymphoma (ATLL) is a malignant lymphoproliferative disease associated with a retrovirus infection caused by the human T-cell lymphotropic virus I (HTLV-I). The disease is…
