The Genetics of Hidradenitis Suppurativa
A family history of hidradenitis suppurativa (HS) is reported by about one-third of patients, and the pattern of inheritance suggests a single gene disorder inherited as an autosomal dominant trait….
The Handicap of Hidradenitis Suppurativa
Hidradenitis suppurativa (HS) is a chronic skin disease, with painful, foul-smelling, recurring inflammation, leading to a diminished quality of life. Patients with HS also often suffer from depression, have an…
Diagnosing Hidradenitis Suppurativa
Three diagnostic criteria must be met for hidradenitis suppurativa: typical lesions, occurrence in one or more of the predilection areas, and that it is chronic and/or recurrent. Several outcome measures…
Prevalence, Risk Factors, and Comorbidities of Hidradenitis Suppurativa
It is challenging to estimate a true prevalence of hidradenitis suppurativa (HS) because it is underdiagnosed and misdiagnosed. Prevalences have been reported from 0.00033% to 4.1%. The incidence seems to…
The Secret Scourge
Gregor B.E. Jemec, MD, DMSc, Editor Some diseases have a greater impact than others. Hidradenitis suppurativa (HS) is a high-impact disease, not only due to its signs and symptoms but…
BRAF Mutations in Erdheim-Chester Disease
Erdheim-Chester disease (ECD) is a xanthogranulomatous disease with variable manifestations that can also severely involve the orbit. In their recent article, “Adult orbital xanthogranulomatous disease: a review with emphasis on…
