Skin and Gut Microbiome

Jun 18, 2022 by in Dermatology Comments Off on Skin and Gut Microbiome

Key points • The human microbiome consists of a wide variety of microorganisms that assist in key physiologic processes. • The majority of microbial diversity is found on the skin…

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Skin Barrier

Jun 18, 2022 by in Dermatology Comments Off on Skin Barrier

Key points • The four layers of the epidermis—stratum corneum, stratum granulosum, stratum spinosum, and stratum basale—are composed of keratinocytes, which undergo differentiation and mature as they become more superficial…

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Epidemiology

Jun 18, 2022 by in Dermatology Comments Off on Epidemiology

Key points • Atopic dermatitis is one of the most common inflammatory diseases of the skin, with both genetic and environmental etiologies. • The prevalence of atopic dermatitis is increasing…

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Atopy Redefined

Jun 18, 2022 by in Dermatology Comments Off on Atopy Redefined

Key points • Although the original term atopy provides a general framework of understanding about allergic clinical conditions, this big umbrella now includes a group of patients who have heterogeneous…

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Historic Perspective

Jun 18, 2022 by in Dermatology Comments Off on Historic Perspective

Key points • From the historic perspective, atopic dermatitis has gone through several evolutionary periods of understanding and development. • From ancient times to the 18th century, medical communities started…

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