Disorders of the Sebaceous and Sweat Gland
Fig. 8.1 A patient with papules and closed comedones consistent with mild acne Fig. 8.2 Combined inflammatory papules with closed comedones and scarring in a patient with moderate acne Fig….
Dermatology
Light-Based Procedures in Pediatric Dermatology
Therapy Blue light Green light Turquoise light Therapy protocol Protective eyewear Daily until safe bilirubin levels are established Table 27.1 First line Neonatal hyperbilirubinemia B Light-Emitting Diode (LED) LED is…
Pearls for Pediatric Dermatologic Procedures
Pearl Apply ethyl chloride vapocoolant spray to the area of skin just prior to skin tag removal. (B) [1] Procedure technique Apply topical anesthetic and/or local anesthetic to the skin…
Bites and Infestations
For diagnosis Clinical examination for classic-appearing burrows, often with a vesicle or small pustule at the end of a burrow Skin scraping with mineral oil for microscopic identification of mites,…
Histiocytoses and Malignancy
Diagnostic Skin Biopsy, preferably excisional sent for: Histology Immunohistochemistry Evaluation Baseline studies of complete blood count (CBC), complete metabolic panel (CMP), gamma glutamyl transferase (GGT), INR/PT, APTT/PTT, fibrinogen, early morning…
Overview of Dermatologic Care in Children
Evaluation Prior to first bath after birth, measure temperature, oxygen status, respiratory rate and heart rate and ensure these signs are stable for 2–4 h Therapies [3, 6, 9, 11]…
Basic Mathematics in Skin Absorption
Symbol Generic units Description A m2 Area of application AUC kg/m3 Area under the curve c kg/m3 Concentration c ss kg/m3 Steady-state concentration C 0 kg/m3 Initial concentration at Cl…
The Effects of Vehicle Mixtures on Transdermal Absorption: Thermodynamics, Mechanisms, Assessment, and Prediction
, where R is the ideal gas constant, T and P are temperature and pressure, x i is the mole fraction of component i, N j are the numbers of…
High Throughput Screening of Transdermal Penetration Enhancers: Opportunities, Methods, and Applications
Fig. 8.1 Schematic of the INSIGHT screening apparatus. The INSIGHT screen is made up of a donor array (top) and a symmetric receiver array (bottom). A single screen can screen…
Non-formulation Parameters That Affect Penetrant-Skin-Vehicle Interactions and Percutaneous Absorption
Fig. 4.1 Schematic illustration of skin (showing epidermis, dermis, hypodermis and skin appendages) and underlying muscles and joints, showing targets of drugs and cosmetics applied to skin for local, systemic…
