Pathogenesis of Melasma
Fig. 4.1 Immunostaining for NKI-beteb and tyrosinase-related protein (TRP)-2 before and after treatment with a combination of soybean extract and niacinamide for 8 weeks. Immunostaining for (a) NKI-beteb before treatment…
Dermatology
Melanogenesis and New Signaling Regulators for the Treatment of Melasma
Fig. 11.1 Schematic depiction of melanogenesis in melanocytes. Tyrosinase (TYR), a key enzyme in melanogenesis, tyrosinase-related protein-1 (TRP-1), dopachrome tautomerase (DCT), and PMEL17 are melanogenesis-related proteins involved in pigmentation disorders,…
What’s in the Pipeline for Melasma and Vitiligo
Topicals Chemical peels Lasers and lights Transdermal drug delivery modes Retinoids Glycolic acid ND:Yag (QS and long pulsed) Skin needling Hydroquinone Salicylic acid QS ruby Microneedling Corticosteroids Jessner’s QS alexandrite…
Camouflage for Brown Skin with Melasma or Vitiligo
Fig. 32.1 Vitiligo on the hands (a), camouflaged with application of dihydroxyacetone (b) Frequent applications of DHA are required to maintain desired effect as the normal epidermal turnover exfoliates the…
Vitiligo and Quality of Life
© Springer India 2017Evangeline B. Handog and Maria Juliet Enriquez-Macarayo (eds.)Melasma and Vitiligo in Brown Skin10.1007/978-81-322-3664-1_30 30. Vitiligo and Quality of Life Marcia Ramos-e-Silva1 , Felipe Cupertino de Andrade1 and João Paulo Niemeyer-Corbellini1 (1) Sector of Dermatology and Post-Graduation Course, University Hospital…
Phototherapy in Vitiligo
Fig. 29.1 Phototherapy algorithm. BSA body surface area, CS corticosteroids, CI calcineurin inhibitors, NB-UVB narrowband ultraviolet B Table 29.1 Combinations in phototherapy Author (year) N Type of trial Therapy combined…
Prevalent Skin Disorders in Brown Skin
© Springer India 2017Evangeline B. Handog and Maria Juliet Enriquez-Macarayo (eds.)Melasma and Vitiligo in Brown Skin10.1007/978-81-322-3664-1_2 2. Prevalent Skin Disorders in Brown Skin Maria Juliet Enriquez-Macarayo1 and Evangeline B. Handog2 (1) Dermatology Department, Angeles University Foundation Medical Center, Angeles…
Topical Medications in Vitiligo
Drug Mechanism of action Level of evidence Corticosteroids Modulate the immune response by reducing the macrophages and T cells Reduce autoantibodies Inhibit complement-mediated melanocyte destruction IA Calcineurin inhibitors Reduce the…
Oral Medications in Vitiligo
© Springer India 2017Evangeline B. Handog and Maria Juliet Enriquez-Macarayo (eds.)Melasma and Vitiligo in Brown Skin10.1007/978-81-322-3664-1_27 27. Oral Medications in Vitiligo Koushik Lahiri1 and Samujjala Deb2 (1) Apollo Gleneagles Hospitals, WIZDERM, Greenwood Nook, Coral Isle-14 RB, 369/2…
Comorbidities in Vitiligo
1. Autoimmune disorders 1.1 Systemic diseases Hashimoto thyroiditis Myasthenia gravis Graves’ disease Sjögren’s syndrome Systemic lupus erythematosus (SLE) Inflammatory bowel disease (IBD) Rheumatoid arthritis 1.2 Dermatoses Alopecia areata 1.3 Autoimmune…
