Innovative Uses of Rituximab in Dermatology
Since its approval in 1997 by the US Food and Drug Administration, rituximab has been approved for use in certain B-cell lymphomas and treatment-resistant rheumatoid arthritis. Over the past 10…
Dermatology
Innovative Use of Topical Calcineurin Inhibitors
Topical tacrolimus and pimecrolimus are indicated for treatment of atopic dermatitis, but they have been studied in many off-label uses. Double-blind and open studies have shown favorable results with topical…
Innovative Use of Topical Metronidazole
Metronidazole is a synthetic nitroimidazole derivative with antimicrobial and antiinflammatory properties. It was the first topical therapy approved solely for rosacea and remains a cornerstone of rosacea management. This article…
Biologic Drugs for the Treatment of Hidradenitis Suppurativa: An Evidence-Based Review
There are various treatment options for hidradenitis suppurativa (HS), a recurrent and suppurative disease, but none is wholly satisfactory or effective. There have been many reports on the efficacy of…
Innovative Therapy of Cutaneous T-Cell Lymphoma: Beyond Psoralen and Ultraviolet Light and Nitrogen Mustard
Cutaneous T-cell lymphoma is a malignancy of skin-homing T cells. This unique population of lymphocytes requires alternative therapies to those used in nodal lymphomas. Although phototherapy and nitrogen mustard have…
Innovative Management of Lupus Erythematosus
This article focuses on the management of discoid lupus erythematosus, subacute cutaneous lupus erythematosus, and systemic lupus erythematosus when the usual therapeutic arsenal such as oral antimalarial drugs and topical/oral…
Innovative Management of Recurrent Furunculosis
One of the most common bacterial infections of the skin and soft tissue is furunculosis (boil), an inflammatory nodule that involves the hair follicle, with small abscess formation extending through…
Innovative Management of Pruritus
Pruritus remains a significant problem facing dermatologists and can be associated with various dermatoses and systemic derangements. At times, one can treat the underlying cutaneous or systemic process to alleviate…
Innovative Management of Severe Hand Dermatitis
The successful treatment of hand dermatitis (HD) depends less on the selection of the proper topical steroid or a particular systemic agent than on addressing any underlying cause or perpetuating…
Extramammary Paget’s Disease: Summary of Current Knowledge
Extramammary Paget’s disease (EMPD) is a rare cutaneous malignancy accounting for approximately 1% of vulvar cancers. The rarity of this disease has caused difficulties in its characterization. Controversies exist in…
