Severe psoriasis is uncommon in children, but when it occurs, can be physically, emotionally and socially disabling. Systemic treatments such as phototherapy, acitretin, methotrexate and cyclosporine have been used to…
Accurate characterization of vascular anomalies is important in predicting clinical course and guiding treatment. This article provides an imaging review of vascular anomalies, highlighting the particular imaging characteristics of hemangiomas…
This article reviews some of the recent literature on therapeutic modalities and their efficacy in common pediatric skin conditions. Immunotherapy and laser therapy of warts and molluscum contagiosum show therapeutic…
This article outlines the epidemiology, pathogenesis, clinical presentation, diagnosis, and treatment of childhood morphea. Also known as localized scleroderma, morphea is a fibrosing disorder of the skin and subcutaneous tissues….
Dermatitis is a frequent cause for referral to the pediatric dermatologist. In this article, a brief overview is given of common childhood dermatoses as well as some rarer dermatoses that…
Skin disease is highly prevalent in the United States, and it has been well-documented that patients with skin disease experience financial, psychological, social, and quality-of-life (QoL) burdens beyond those of…
The continuous advance in the search for the cause and pathogenesis of the autoinflammatory syndromes, as well as reports of the efficacy of specific inflammation-mediator suppressors, has changed the way…
The recent molecular, biologic, and genetic understanding of the inflammasome has revolutionized the diagnosis of and therapy for the phenotypically heterogeneous group of rare oligogenic disorders, now recognized to have…
Autoinflammatory diseases (AIDs) are characterized by recurrent episodes of systemic and organ-specific inflammation. Many of these diseases share fever as a common presenting feature. Physicians need to consider AIDs in…
Autoinflammatory syndromes comprise a diagnostically challenging group of systemic inflammatory disorders uniquely related by (1) dysregulation of innate immunity, (2) inflammasome activation, (3) dramatic clinical features (high fevers, neutrophilic rashes,…
