S. No Enhancement method Technology Manufacturer Drug 1 Iontophoresis E-Trans® Alza Fentanyl 2 Iontophoresis Iontophoretic drug delivery system Iomed® Lidocaine and epinephrine 3 Microporation Microstructured transdermal system 3 M Hydrophilic…
© Springer-Verlag Berlin Heidelberg 2017Nina Dragicevic and Howard I. Maibach (eds.)Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin10.1007/978-3-662-53270-6_18 18. Retardation Strategies for Sunscreen Agents Katharina Bohnenblust-Woertz1 and Christian Surber2, 3 (1) Galderma Spirig, Egerkingen, Switzerland (2) University…
Fig. 17.1 Corneoxenometry. Aspect of a cyanoacrylate skin surface stripping stained by a toluidine blue-basic fuchsine after contact with a penetration enhancer. The staining of corneocytes is uneven and indicates…
Fig. 14.1 ATR-FTIR spectrum of porcine ear skin recorded at 32 °C, showing the typical skin bands Although it represents a very basic and simplified model of the human skin…
Fig. 8.1 Breadloaf technique. (a) Standard excision processed with breadloaf technique (Image ©2016, Memorial Sloan Kettering Cancer Center. Used with permission). (b) Melanoma excised with standard margin as an ellipse….
Fig. 16.1 Biopsy proven lentigo maligna melanoma with ill-defined clinical borders Fig. 16.2 Wood’s light examination of pigmented lesion Fig. 16.3 Dermoscopic examination of pigmented lesion Fig. 16.4 Reflectance confocal…
Study Recurrence rate 95 % CI % weight Lower Upper Excision Pitman [34] 0.09 0.01 0.29 2.31 Hill [35] 0.02 0 0.08 3.05 Argawal-Antal [36] 0 0 0.04 3.2 Osborne…
Fig. 10.1 (a–g) Left cheek lentigo maligna with final defect much larger than anticipated Several studies have reported reconstruction techniques that were used following excision of LM/LMM. In the above…
Fig. 9.1 (a) Histology of normal eyelid skin; (b) Eyelid melanoma, 1.7 mm breslow thickness The eyelid is made up of three functional lamellae, the anterior lamella which includes the…
Fig. 4.1 Dermoscopy image of lentigo maligna melanoma on the cheek displaying an annular-granular pattern composed of gray and brown dots asymmetrically distributed around follicular openings UVR damaged skin of…
