Keratoacanthoma
Histology: The tumor is typically a cup-shaped exophytic nodule that has a prominent keratin-filled plug. The borders of the tumor are well circumscribed. The tumor is symmetric. Neutrophilic abscesses within…
Mammary and Extramammary Paget’s Disease
Treatment: The prognosis for extramammary Paget’s disease depends on the stage of the tumor. Disease that is localized to the skin has an excellent prognosis. The treatment of choice is…
Kaposi’s Sarcoma
Histology: Biopsies of Kaposi’s sarcoma show many characteristic findings. The promontory sign is often seen; it is represented by plump endothelial cells jutting into the lumen of the capillary vessel….
Dermatofibrosarcoma Protuberans
Histology: Dermatofibrosarcoma protuberans shows an infiltrative growth pattern. It invades the subcutaneous fat tissue. The tumor cells can be seen encasing adipocytes. The tumor is poorly circumscribed, and its borders…
Cutaneous Metastases
Histology: The diagnosis of cutaneous metastasis is almost always made by the pathologist after histological review. Each tumor is unique, and the histological picture depends on the primary tumor. Treatment:…
Bowenoid Papulosis
Treatment: After biopsy has ruled out an invasive component to this tumor, the main treatment of bowenoid papulosis is to clinically remove the areas of involvement. The importance of decreasing…
Basal Cell Carcinoma: Clinical and Histological Evaluation
Medical therapy with imiquimod or 5-fluorouracil has also been shown to be useful in selected BCCs, usually the small, superficial type. One of the newest treatments is photodynamic therapy. It…
Bowen’s Disease
Treatment: Treatments can be divided into surgical and nonsurgical forms. The choice depends on various factors, most importantly the location and size of the lesion. Some tumors are best treated…
Basal Cell Carcinoma: Basic Facial Anatomy
The most important genetic syndrome associated with the development of BCCs is the nevoid BCC syndrome. This syndrome is inherited in an autosomal dominant fashion and is caused by a…
Angiosarcoma
Histology: All angiosarcomas share the same pathological features. The tumor lobules are poorly circumscribed and have an infiltrative growth pattern. They contain large amounts of vascular tissue in a disorganized…
