Leukocytoclastic Vasculitis
Treatment: Therapy is based on the cause of the leukocytoclastic vasculitis. New offending medications should be withdrawn and replaced with substitutes of a different class. Infections need to be thoroughly…
Langerhans Cell Histiocytosis: Eosinophilic Granuloma
Multisystem disease is treated in myriad manners, depending on the burden of disease, the systemic involvement, and the patient’s symptoms. The disease can be difficult to treat, and systemic chemotherapies…
Keratosis Pilaris
Treatment: No therapy is required for most cases. A keratolytic moisturizer or humectant moisturizer works well. These include lactic acid– and salicylic acid–based moisturizers. After discontinuation, however, the rash of…
Langerhans Cell Histiocytosis: Presentation in Childhood
Twenty percent of patients do not exhibit any cutaneous signs of disease and present solely with varying systemic complaints. The most common extracutaneous form of LCH, formerly designated eosinophilic granuloma,…
Irritant Contact Dermatitis
Treatment: The goal of treatment is to remove the skin from exposure to the irritant. Barrier creams and frequent diaper changes may be all that is needed to resolve irritant…
Hidradenitis Suppurativa (Acne Inversa)
Treatment: Therapy is often aimed at reducing inflammation and bacterial superinfection. There is no curative therapy, and most treatments have only anecdotal reports of success. Topical clindamycin and other antibacterial…
Granuloma Annulare
Treatment: Localized forms of granuloma annulare that are asymptomatic and not causing any distress to the patient can be left alone. Most cases resolve spontaneously over time with no residual…
Graves Disease and Pretibial Myxedema
Treatment: Treatment of Graves’ disease is predicated on stopping the excessive thyroid hormone production. Ablation of the thyroid can be achieved with radiation therapy or surgical removal. Medications such as…
Graft-versus-Host Disease
Chronic GVHD is difficult to manage. There is no cure for GVHD, and treatment is directed at stabilizing and improving skin function and increasing the patient’s functional capabilities. Phototherapy has…
Gout: Tophaceous Gout
Tophi can be treated with the long-term use of allopurinol or probenecid. Over time, the goal is to mobilize the tissue uric acid and increase its excretion from the body….
