Skin Changes in Menopause
Vitamin D PTHrP Estrogens Androgens T3 MSH ACTH TRH GH The skin cells contain the entire biochemical apparatus necessary for production of glucocorticoids, androgens, and estrogens either from precursors of…
Vitamin D PTHrP Estrogens Androgens T3 MSH ACTH TRH GH The skin cells contain the entire biochemical apparatus necessary for production of glucocorticoids, androgens, and estrogens either from precursors of…
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Skin structure Sex steroid receptors AR PR ER-α ER-β Epidermal keratinocytes + + + Melanocytes + + + Hair follicles Follicular keratinocytes + + Root sheath + Matrix epithelium + …
Skin layer Cellular element Cytokines Epidermis Keratinocyte TNF-α [1], IL-1α [34], IL-1ra [34], IL-6 [47], IL-8 [60], IL-10 [67] Langerhans cell IL-8 [60], IL-18 [33] Melanocyte IL-8 [60] Dermis Fibroblast…