Cutaneous Lymphomas

Oct 6, 2016 by in Dermatology Comments Off on Cutaneous Lymphomas

Fig. 29.1 Electron microscopy of a malignant T cell in a patient with Sézary syndrome with characteristic prominent polychromatic cerebriform nucleus. Scale bar 2 μm From an immunological perspective, patients with…

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C-Type Lectin Receptors

Oct 6, 2016 by in Dermatology Comments Off on C-Type Lectin Receptors

Fig. 17.1 Domain structure for the traditional seven (I–VII) groups of vertebrate CTLs. Domain names are listed in the box The natural killer (NK) receptor family (group V) contains a…

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B Cells

Oct 6, 2016 by in Dermatology Comments Off on B Cells

Fig. 7.1 B cell development, subset, and differentiation. In the bone marrow, the B cell lineage cell starts as the pro-B cell, which differentiates into the pre-B cell expressing the…

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Adipose Tissues

Oct 6, 2016 by in Dermatology Comments Off on Adipose Tissues

Fig. 15.1 Role of the immune system in obese versus lean adipose tissue. In obese adipose tissue, Th1-type cytokines such as IFN-γ stimulate M1 macrophage polarization. Mast cells are also…

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Contact Dermatitis

Oct 6, 2016 by in Dermatology Comments Off on Contact Dermatitis

Fig. 20.1 Representative image of neutrophil infiltration and T cells–DCs interaction in skin during elicitation phase. (a) Accumulation of neutrophils in dermis 24 h after elicitation (Green: neutrophils in Lysm-eGFP mice….

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Psoriasis

Oct 6, 2016 by in Dermatology Comments Off on Psoriasis

Fig. 22.1 Cellular components of healthy and inflamed skin. Representative immunohistochemistry of normal appearing, nonlesional skin of psoriasis patients, and lesional psoriasis skin, and summary of immune cellular components and…

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Collagen Vascular Disease

Oct 6, 2016 by in Dermatology Comments Off on Collagen Vascular Disease

© Springer Japan 2016Kenji Kabashima (ed.)Immunology of the Skin10.1007/978-4-431-55855-2_31 31. Collagen Vascular Disease Yoshihide Asano1   (1) Department of Dermatology, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan     Yoshihide Asano Email:…

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Rosacea in Skin Innate Immunity

Oct 6, 2016 by in Dermatology Comments Off on Rosacea in Skin Innate Immunity

© Springer Japan 2016Kenji Kabashima (ed.)Immunology of the Skin10.1007/978-4-431-55855-2_28 28. Rosacea in Skin Innate Immunity Kenshi Yamasaki1   (1) Department of Dermatology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai Miyagi, 980-8574, Japan    …

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Macrophages

Oct 6, 2016 by in Dermatology Comments Off on Macrophages

Marker Function Comments Classically activated macrophage (M1 macrophage) IL-6 Promotes inflammatory response Induced by IFN-γ IL-12 Induces Th1 development Induced by IFN-γ iNOS Produces NO to kill microorganisms Induced by…

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