Negative Pressure Wound Therapy
Negative pressure wound therapy (NPWT) has overwhelmed the wound-healing world. A systematic review puts it into perspective. The authors have developed an algorithm after careful evaluation and analysis of the…
General Surgery
Oxygen in Wound Healing
Disturbances to healing observed under hypoxic conditions have given insights into the roles of oxygen. Wound hypoxia is more prevalent than generally appreciated, and occurs even in patients who are…
Early Experiences with Stem Cells in Treating Chronic Wounds
This review provides a thorough and clear discussion on the outcomes of stem cells in treating chronic wounds. With recent technological developments that now allow isolation and culture of stem…
Compression and Venous Surgery for Venous Leg Ulcers
This article reviews published data on the effects of surgery and compression in the treatment of venous ulcers and the best options for compression therapy. Randomized controlled studies reveal that surgery…
Regenerative Materials That Facilitate Wound Healing
Wounds and damaged tissue become problematic when the tissue repair process does not proceed in a normal manner. Standard treatment of wounds entails topical dressings and devices in conjunction with…
Harnessing Growth Factors to Influence Wound Healing
Cutaneous wound healing is a dynamic process with the ultimate goal of restoring skin integrity. On injury to the skin, inflammatory cells, endothelial cells, fibroblasts, and keratinocytes undergo changes in…
Microbial Barriers
Barrier wound therapy is commonplace in the health care environment and functions to limit bacterial colonization and infection in both acute wounds and recalcitrant chronic wounds. This article reviews the…
Debridement of Chronic Wounds
This article reviews the current evidence available regarding wound debridement of chronic wounds and collates data from existing randomized controlled trials. • Routine use of debridement in the treatment of…
Plastic Surgery’s Critical Role in Wound Management
Mark S. Granick, MD, Guest Editor I have edited a number of issues of Clinics in Plastic Surgery relating to wound issues: 1993 Management of Radiation Wounds, 1998 Wound Healing:…
