Pathogenesis: The pathogenesis of these cutaneous manifestations of inflammatory bowel disease is unknown. They are theorized to be caused by an autoimmune mechanism of defective cell-mediated immunity. Metastatic Crohn’s disease…
Because of its chronic nature, adult seborrheic dermatitis is treated with topical ketoconazole as a first-line therapy. The other azole antifungal agents are just as effective. The addition of a…
Treatment: The treatment for sarcoid has been consistent over time and includes nonspecific immunosuppression, most commonly with oral corticosteroids such as prednisone. Isolated cutaneous findings may be treated with topical…
Treatment: Any underlying infection must be sought and appropriately treated with the correct antibiotic therapy. Nonsteroidal antiinflammatory drugs are used to treat the arthritis. An ophthalmologist should be consulted to…
Lupus pernio is the name given to the clinical findings of specific cutaneous sarcoid involvement of the nose and the rest of the face. This form of sarcoid is quite…
Chronic radiation dermatitis, in and of itself, does not require therapy unless the patient experiences severe tightness or hardness of the skin. In anecdotal reports, pentoxifylline has been successful in…
Oral systemic agents are also used for moderate to severe psoriasis. Methotrexate taken on a weekly basis has been used for years. Oral cyclosporine has been used with great success…
Pathogenesis: Psoriasis is an autoimmune disease caused by an abnormality within the cells of the immune system. There is a genetic susceptibility, and the human leukocyte antigen (HLA) Cw6 locus…
Guttate psoriasis is a variant of psoriasis that can occur after an infection, most notably a streptococcal bacterial infection. The guttate lesions develop soon after or during the infection and…
