Pigmented Purpura
Treatment: There is no agreed-upon standard therapy, and withholding therapy is a frequently used option. Anecdotally, topical corticosteroids may be tried for a few weeks. Oral vitamin C and bioflavonoids…
Dermatology
Phytophotodermatitis
Treatment: Acute areas of involvement can be treated with topical corticosteroid creams. The main issue in management is dealing with the prolonged postinflammatory hyperpigmentation. No therapy has been shown to…
Oral Manifestations in Blood Dyscrasias
TTP is a rare, life-threatening disease that can develop rapidly. It is manifested by the formation of microthrombi throughout the small vasculature. This causes multisystem organ failure and rapid death…
Ochronosis: Systemic Findings
Treatment: No known cure is available, and there is no effective therapy. Physical therapy and joint replacement increase flexibility and range of motion and help to decrease morbidity. Some researchers…
Ochronosis: Metabolic Pathway and Cutaneous Findings
As the homogentisic acid accumulates in these patients, it eventually begins depositing in skin and cartilage tissue, for which it has an affinity, becoming visibly noticeable in the fourth decade…
Neutrophilic Eccrine Hidradenitis
Treatment: Treatment is supportive. Underlying infections need to be treated adequately. The main goals are pain control and prevention of secondary infection. If the patient’s neutrophilic eccrine hidradenitis is caused…
Necrobiotic Xanthogranuloma
Treatment: Therapy is difficult. No randomized prospective studies have been performed on this rare condition, so only anecdotal therapies have been reported. Topical and oral steroids have been somewhat successful….
Necrobiosis Lipoidica
Treatment: Treatment is typically initiated with the use of high-potency topical steroids. It may seem counterintuitive to treat an atrophic condition with topical corticosteroid creams, which can cause atrophy. In…
