Fig. 24.1 (a) The hapten-modified peptide is recognized and stimulates T cells. The hapten may also have the ability to activate the innate immune system. (b) The drug binds to…
Fig. 2.1 Epidermal structures. Insert, electron micrograph: Murine skin was fixed in Karnovsky’s fixative overnight, and postfixed with 0.25 % ruthenium tetroxide. Ultrathin sections were examined using an electron microscope 2.2…
Fig. 4.1 Cutaneous dendritic cells in the steady state and in the inflammatory state. LCs Langerhans cells, dermal DCs dermal dendritic cells, IDECs inflammatory dendritic epidermal cells, Tip-DCs tumor necrosis…
Fig. 13.1 The structure of the hair follicle and the hair cycle. Fully grown anagen hair follicle extends deeper into subcutaneous fat. Anagen hair follicle is divided into five anatomical…
Fig. 6.1 Dendritic epidermal T cells (DETCs). Epidermal sheet from a normal adult mouse stained with an anti-γδ TCR monoclonal antibody (green, DETCs) and DAPI (blue, mainly keratinocytes) Unlike conventional…
Fig. 9.1 Neutrophils in the skin. Schematic representation of molecular and cellular processes initiated during neutrophil antibacterial response in the dermis. The antibacterial response is initiated by sensing of DAMPs…
Fig. 12.1 Lymphatic vessels and valves shown by enhanced green fluorescent protein driven by Prox1 promoter in transgenic mice. (a) Cutaneous lymphatic vessels are found in dorsal skin 1 week after…
(1) Department of Dermatology, University of Pennsylvania, Penn Presbyterian Medical Center Medical Arts Building, Philadelphia, PA, USA 17.1 Procedures and Cosmetics 17.1.1 Neurotoxins 17.1.2 Fillers 17.1.3 Peels 17.1.4 Lasers…
(1) Department of Dermatology, University of Pennsylvania, Penn Presbyterian Medical Center Medical Arts Building, Philadelphia, PA, USA 18.1 Keratinocyte Adhesion 18.2 Basement Membrane 18.3 Cornified Envelope 18.4 Extracellular Matrix…
(1) Department of Dermatology, University of Pennsylvania, Penn Presbyterian Medical Center Medical Arts Building, Philadelphia, PA, USA 16.1 Systemic Immunosuppressants and Anti-inflammatory Agents 16.2 Cytotoxic Medications and Chemotherapy Agents…
