Stearoyl-CoA Desaturases are Regulators of Lipid Metabolism in Skin
Bonet ML, Ribot J, Felipe F, Palou A. Vitamin A and the regulation of fat reserves. Cell Mol Life Sci. 2003;7:1311–21.CrossRef Cases S, Stone SJ, Zhou P, Yen E, Tow…
Dermatology
Adipose Tissue and Fat Cell Biology
Brooks BJ. Studies on the triglyceride—fatty acid cycle. Oxford: Merton College; 2013. Brown NF, Hill JK, Esser V, Kirkland JL, Corkey BE, Foster DW, McGarry JD. Mouse white adipocytes and…
Squalene Chemistry and Biology
Fig. 12.1 Linear (Ia) and folded (Ib) structures of squalene (I) and structure of 2,3-oxidosqualene (II, squalene epoxide). Squalene is transformed into several oxygenated derivatives and breakdown compounds by different…
Sebaceous Lipids
Lipid class Range weight, % Mean weight, % Triglycerides 20–60 45 Wax esters 23–29 25 Squalene 10–14 12 Free-fatty acids 5–40 10 Cholesterol and sterol esters 1–5 4 Diglycerides 1–2…
Nuclear Hormone Receptors and Epidermal Differentiation
Fig. 7.1 Keratinocyte differentiation involves changes in the protein and lipid composition of different epidermal layers. Epidermal proliferation and differentiation are essential for the formation of the cornified layer and…
Skin Lipids: An Introduction and Their Importance
© Springer Science+Business Media New York 2015Apostolos Pappas (ed.)Lipids and Skin Health10.1007/978-3-319-09943-9_1 1. Skin Lipids: An Introduction and Their Importance Apostolos Pappas1 (1) The Johnson & Johnson Skin Research Center, CPPW, a division of Johnson…
Skin Ceramides
Fig. 5.1 Structures of human stratum corneum ceramides (Ponec et al. 2003) accompanied by shorthand nomenclature (Motta et al. 1993). Ceramides are arranged from least polar at the top of…
Emergence of Virulent Staphylococci Overriding Innate Immunity of Skin in Communities
Fig. 18.1 History of methicillin-resistant Staphylococcus aureus Looking back at the history of ß-lactam resistance of S. aureus, we notice we have experienced emergence of three generations of MRSA. The…
Keratinocytes
Fig. 3.1 Overview of epidermal keratinocytes in innate immunity. The keratinocyte is the first cell to come in contact with and sense pathogens. Keratinocytes detect gram-positive bacteria and virus-associated double-stranded…
