Dermatology

Skin and Effect of Hormones and Menopause

Nov 3, 2016 by in Dermatology Comments Off on Skin and Effect of Hormones and Menopause

Skin structure Sex steroid receptors AR PR ER-α ER-β Epidermal keratinocytes + + +  Melanocytes +  + + Hair follicles     Follicular keratinocytes +  +  Root sheath   +  Matrix epithelium + …

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The Effect of Cytokines on Skin During Menopause

Nov 3, 2016 by in Dermatology Comments Off on The Effect of Cytokines on Skin During Menopause

Skin layer Cellular element Cytokines Epidermis Keratinocyte TNF-α [1], IL-1α [34], IL-1ra [34], IL-6 [47], IL-8 [60], IL-10 [67] Langerhans cell IL-8 [60], IL-18 [33] Melanocyte IL-8 [60] Dermis Fibroblast…

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Desmoplastic Melanoma

Oct 15, 2016 by in Dermatology Comments Off on Desmoplastic Melanoma

Fig. 46.1 Desmoplastic melanoma. An ill-defined indurated plaque on the back of a 60-year-old female. Pigmentation and signs of regression suggest the diagnosis Fig. 46.2 Desmoplastic melanoma. A painful and…

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Spitzoid Melanoma

Oct 15, 2016 by in Dermatology Comments Off on Spitzoid Melanoma

Fig. 52.1 Spitzoid melanoma. An erythematous fast-growing nodule on the upper arm of a 49-year-old man Pathology Spitzoid melanoma shares many histopathologic features with Spitz nevus, and it is one…

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Cutaneous Metastases of the Gastrointestinal Tract

Oct 15, 2016 by in Dermatology Comments Off on Cutaneous Metastases of the Gastrointestinal Tract

Fig. 72.1 Cutaneous metastases from gastric carcinoma. An erythematous plaque around a scar from excision of a primary neoplasm Fig. 72.2 Cutaneous metastases from colon adenocarcinoma. Sister Mary Joseph’s periumbilical…

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Primary Cutaneous Rhabdomyosarcoma

Oct 15, 2016 by in Dermatology Comments Off on Primary Cutaneous Rhabdomyosarcoma

Fig. 43.1 PC-RMS is a multinodular proliferation of atypical round or spindle cells centered in the dermis and/or subcutis Fig. 43.2 The tumor cells are arranged in nodules and sheets…

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Cutaneous Metastases of Breast Carcinoma

Oct 15, 2016 by in Dermatology Comments Off on Cutaneous Metastases of Breast Carcinoma

Fig. 71.1 Cutaneous metastases of breast carcinoma. Warm, erythematous patches and plaques surrounding the sectorectomy scar for breast carcinoma Fig. 71.2 Cutaneous metastases of breast carcinoma. Multiple tumors with a…

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